Invasive Carcinoma With Skin Adnexal Trichilemmal Hair Follicular Differentiation Occurring in the Breast: A Case Report With Detailed Immunohistochemical and Molecular Analysis

Overview

Journal Int J Surg Pathol

Publisher Sage Publications

Specialties General Surgery
Pathology

Date 2023 Aug 1

PMID 37525555

Authors

Oluwaseyi Olayinka

Solange E Cox

Azadeh Nasrazadani

Erika Resetkova

Doina Ivan

Lavinia P Middleton

Affiliations

Soon will be listed here.

Abstract

Cutaneous-type adnexal tumors involving the breast are rare and create a diagnostic dilemma as they are often indistinguishable from primary mammary neoplasms. Tumors showing hair follicular differentiation are particularly challenging due to their rarity and the subtle appreciation of the intricate microanatomy of the hair follicle. We report a triple negative cutaneous-type adnexal carcinoma with follicular differentiation involving the breast to bring attention to the existence of these specialized group of tumors which should be managed differently from conventional triple negative carcinomas of the breast.

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