An Unusual Presentation of Dermatomyositis With Muscle Hypertrophy

Overview

Journal Cureus

Specialty Biomedical Engineering

Date 2023 Jul 31

PMID 37519595

Authors

George Bailey

Jaya R Trivedi

Affiliations

Soon will be listed here.

Abstract

Peripheral nerve hyperexcitability is a rare disorder characterized by spontaneous motor unit activity. Although peripheral nerve hyperexcitability is seen in multiple immune-mediated neurological conditions, an association with dermatomyositis has rarely been reported. We present a 65-year-old woman with serological and muscle biopsy features of dermatomyositis who also developed marked muscle hypertrophy, stiffness, and delayed relaxation along with electrodiagnostic features of peripheral nerve hyperexcitability such as that seen in Isaacs syndrome.

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