Flexible Processing Technology of Coix Seed Prolamins by Combined Heat-ultrasound: Effects on Their Enzymatic Hydrolysis Characteristics and the Hypoglycemic Activities of Derived Peptides

Overview

Journal Ultrason Sonochem

Specialty Radiology

Date 2023 Jul 29

PMID 37515909

Authors

Zhiming Li

Shu Zhang

Lu Bai

Huacheng Tang

Guifang Zhang

Jiayu Zhang

Weihong Meng

Dongjie Zhang

Affiliations

Soon will be listed here.

Abstract

The self-assembled structures of coix seeds affected the enzymatic efficiency and doesn't facilitate the release of more active peptides. The influence of heating combined with ultrasound pretreatment (HT + US) on the structure, enzymatic properties and hydrolysates (CHPs) of coix seed prolamin was investigated. Results showed that the structural of coix seed prolamins has changed after HT + US, including increased surface hydrophobicity, reduced α-helix and random coil content, and a decrease in particle size. So that, leads to changes in thermodynamic parameters such as an increase in the reaction rate constant and a decrease in activation energy, enthalpy and enthalpy. The fractions of <1000 Da, degree of hydrolysis and α-glucosidase inhibitory were increased in the HT + US group compared to single pretreatment by 0.68%-17.34%, 12.69%-34.43% and 30.00%-53.46%. The peptide content and α-glucosidase inhibitory activity of CHPs could be maintained at 72.21 % and 57.97 % of the initial raw materials after in vitro digestion. Thus, the findings indicate that HT + US provides a feasible and efficient approach to can effectively enhance the enzymatic hydrolysis efficiency and hypoglycaemic efficacy of CHPs.

Citing Articles

Anti-Type II Diabetic Effects of Coix Seed Prolamin Hydrolysates: Physiological and Transcriptomic Analyses.

Zhang G, Li Z, Zhang S, Bai L, Zhou H, Zhang D Foods. 2024; 13(14).

PMID: 39063287 PMC: 11275950. DOI: 10.3390/foods13142203.

Screening and Activity Analysis of α-Glucosidase Inhibitory Peptides Derived from Coix Seed Prolamins Using Bioinformatics and Molecular Docking.

Li Z, Zhang S, Meng W, Zhang J, Zhang D Foods. 2023; 12(21).

PMID: 37959088 PMC: 10649794. DOI: 10.3390/foods12213970.

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