Prevention and Treatment of Retinal Vein Occlusion: The Role of Diet-A Review

Overview

Journal Nutrients

Date 2023 Jul 29

PMID 37513655

Authors

Maja Lendzioszek

Malgorzata Mrugacz

Anna Bryl

Ewa Poppe

Katarzyna Zorena

Affiliations

Soon will be listed here.

Abstract

Retinal vein occlusion (RVO) is the second most common retinal disorder. In comparison to diabetic retinopathy or age-related macular degeneration, RVO is usually an unexpected event that carries a greater psychological impact. There is strong evidence to suggest that cardiovascular diseases are the most common risk factors in this pathology and it has long been known that a higher consumption of fish, nuts, fruits, and vegetables has a protective effect against these types of conditions. In the last several years, interest in plant-based diets has grown in both the general population and in the scientific community, to the point to which it has become one of the main dietary patterns adopted in Western countries. The aim of this review is to investigate the potential impact of macro- and micronutrients on retinal vein occlusion.

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References

Garcia-Casal M, LAYRISSE M, Solano L, Baron M, ARGUELLO F, Llovera D . Vitamin A and beta-carotene can improve nonheme iron absorption from rice, wheat and corn by humans. J Nutr. 1998; 128(3):646-50. DOI: 10.1093/jn/128.3.646. View

DElia L, Barba G, Cappuccio F, Strazzullo P . Potassium intake, stroke, and cardiovascular disease a meta-analysis of prospective studies. J Am Coll Cardiol. 2011; 57(10):1210-9. DOI: 10.1016/j.jacc.2010.09.070. View

Howard B, Roman M, Devereux R, Fleg J, Galloway J, Henderson J . Effect of lower targets for blood pressure and LDL cholesterol on atherosclerosis in diabetes: the SANDS randomized trial. JAMA. 2008; 299(14):1678-89. PMC: 4243925. DOI: 10.1001/jama.299.14.1678. View

Hunt J . Bioavailability of iron, zinc, and other trace minerals from vegetarian diets. Am J Clin Nutr. 2003; 78(3 Suppl):633S-639S. DOI: 10.1093/ajcn/78.3.633S. View

Weaver C . Potassium and health. Adv Nutr. 2013; 4(3):368S-77S. PMC: 3650509. DOI: 10.3945/an.112.003533. View

Chait A, MALINOW M, Nevin D, Morris C, Eastgard R, Pi-Sunyer F . Increased dietary micronutrients decrease serum homocysteine concentrations in patients at high risk of cardiovascular disease. Am J Clin Nutr. 1999; 70(5):881-7. DOI: 10.1093/ajcn/70.5.881. View

Martin S, Rauz S, Marr J, Martin N, Jones A, Dodson P . Plasma total homocysteine and retinal vascular disease. Eye (Lond). 2000; 14 ( Pt 4):590-3. DOI: 10.1038/eye.2000.148. View

Grundy S, Cleeman J, Merz C, Brewer Jr H, Clark L, Hunninghake D . Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. J Am Coll Cardiol. 2004; 44(3):720-32. DOI: 10.1016/j.jacc.2004.07.001. View

Moiseyev G, Takahashi Y, Chen Y, Gentleman S, Redmond T, Crouch R . RPE65 is an iron(II)-dependent isomerohydrolase in the retinoid visual cycle. J Biol Chem. 2005; 281(5):2835-40. DOI: 10.1074/jbc.M508903200. View

10.

Kirkham T, Wrigley P, Holt J . Central retinal vein occlusion complicating iron deficiency anaemia. Br J Ophthalmol. 1971; 55(11):777-80. PMC: 1208552. DOI: 10.1136/bjo.55.11.777. View

11.

Brzosko S, De Curtis A, Murzilli S, de Gaetano G, Donati M, Iacoviello L . Effect of extra virgin olive oil on experimental thrombosis and primary hemostasis in rats. Nutr Metab Cardiovasc Dis. 2003; 12(6):337-42. View

12.

Verdoia M, Schaffer A, Sartori C, Barbieri L, Cassetti E, Marino P . Vitamin D deficiency is independently associated with the extent of coronary artery disease. Eur J Clin Invest. 2014; 44(7):634-42. DOI: 10.1111/eci.12281. View

13.

Khayyal M, El-Ghazaly M, Abdallah D, Nassar N, Okpanyi S . Blood pressure lowering effect of an olive leaf extract (Olea europaea) in L-NAME induced hypertension in rats. Arzneimittelforschung. 2002; 52(11):797-802. DOI: 10.1055/s-0031-1299970. View

14.

Schoene N, Chanmugam P, Reynolds R . Effect of oral vitamin B6 supplementation on in vitro platelet aggregation. Am J Clin Nutr. 1986; 43(5):825-30. DOI: 10.1093/ajcn/43.5.825. View

15.

Wenzler E, Rademakers A, Boers G, Cruysberg J, Webers C, Deutman A . Hyperhomocysteinemia in retinal artery and retinal vein occlusion. Am J Ophthalmol. 1993; 115(2):162-7. DOI: 10.1016/s0002-9394(14)73919-4. View

16.

Ghanchi F, Bourne R, Downes S, Gale R, Rennie C, Tapply I . An update on long-acting therapies in chronic sight-threatening eye diseases of the posterior segment: AMD, DMO, RVO, uveitis and glaucoma. Eye (Lond). 2022; 36(6):1154-1167. PMC: 9151779. DOI: 10.1038/s41433-021-01766-w. View

17.

Marcucci R, Bertini L, Giusti B, Brunelli T, Fedi S, Cellai A . Thrombophilic risk factors in patients with central retinal vein occlusion. Thromb Haemost. 2001; 86(3):772-6. View

18.

Klein R, Klein B, Knudtson M, Wong T, Tsai M . Are inflammatory factors related to retinal vessel caliber? The Beaver Dam Eye Study. Arch Ophthalmol. 2006; 124(1):87-94. DOI: 10.1001/archopht.124.1.87. View

19.

Haider L, Schwingshackl L, Hoffmann G, Ekmekcioglu C . The effect of vegetarian diets on iron status in adults: A systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2016; 58(8):1359-1374. DOI: 10.1080/10408398.2016.1259210. View

20.

Brondum-Jacobsen P, Benn M, Tybjaerg-Hansen A, Nordestgaard B . 25-Hydroxyvitamin D concentrations and risk of venous thromboembolism in the general population with 18,791 participants. J Thromb Haemost. 2013; 11(3):423-31. DOI: 10.1111/jth.12118. View