Prostate Cancer and Its Mimics-A Pictorial Review

Overview

Journal Cancers (Basel)

Publisher MDPI

Specialty Oncology

Date 2023 Jul 29

PMID 37509343

Authors

Anna Zurowska

Rafal Peksa

Michal Bienkowski

Katarzyna Skrobisz

Marek Sowa

Marcin Matuszewski

Wojciech Biernat

Edyta Szurowska

Affiliations

Soon will be listed here.

Abstract

Background: Multiparametric prostate MRI (mpMRI) is gaining wider recommendations for diagnosing and following up on prostate cancer. However, despite the high accuracy of mpMRI, false positive and false negative results are reported. Some of these may be related to normal anatomic structures, benign lesions that may mimic cancer, or poor-quality images that hamper interpretation. The aim of this review is to discuss common potential pitfalls in the interpretation of mpMRI.

Methods: mpMRI of the prostates was performed on 3T MRI scanners (Philips Achieva or Siemens Magnetom Vida) according to European Society of Urogenital Radiology (ESUR) guidelines and technical requirements.

Results: This pictorial review discusses normal anatomical structures such as the anterior fibromuscular stroma, periprostatic venous plexus, central zone, and benign conditions such as benign prostate hyperplasia (BPH), post-biopsy hemorrhage, prostatitis, and abscess that may imitate prostate cancer, as well as the appearance of prostate cancer occurring in these locations. Furthermore, suggestions on how to avoid these pitfalls are provided, and the impact of image quality is also discussed.

Conclusions: In an era of accelerating prostate mpMRI and high demand for high-quality interpretation of the scans, radiologists should be aware of these potential pitfalls to improve their diagnostic accuracy.

Citing Articles

Positive Predictive Value of High-Grade Prostate Imaging and Reporting Data System V2.1 Magnetic Resonance Imaging Findings for Prostate Cancer.

Mehammed A, Worke A, Buser A, Issa S, Menna T, Legesse T Ethiop J Health Sci. 2024; 34(Spec Iss 1):23-30.

PMID: 39735526 PMC: 11674756. DOI: 10.4314/ejhs.v34i1.5S.

Interpreting Prostate Multiparametric MRI: Beyond Adenocarcinoma - Anatomical Variations, Mimickers, and Post-Intervention Changes.

Yilmaz E, Esengur O, Gelikman D, Turkbey B Semin Ultrasound CT MR. 2024; 46(1):2-30.

PMID: 39580037 PMC: 11741936. DOI: 10.1053/j.sult.2024.11.001.

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