» Articles » PMID: 37504418

-Based Hydrogels for Wound Healing: Properties and Therapeutic Effects

Overview
Journal Gels
Date 2023 Jul 28
PMID 37504418
Authors
Affiliations
Soon will be listed here.
Abstract

-based hydrogels have emerged as promising platforms for the delivery of therapeutic agents in wound dressings due to their biocompatibility and unique wound-healing properties. The present study provides a comprehensive overview of recent advances in the application of -based hydrogels for wound healing. The synthesis methods, structural characteristics, and properties of -based hydrogels are discussed. Mechanisms of therapeutic agents released from -based hydrogels, including diffusion, swelling, and degradation, are also analyzed. In addition, the therapeutic effects of -based hydrogels on wound healing, as well as the reduction of inflammation, antimicrobial activity, and tissue regeneration, are highlighted. The incorporation of various therapeutic agents, such as antimicrobial and anti-inflammatory ones, into -based hydrogels is reviewed in detail. Furthermore, challenges and future prospects of -based hydrogels for wound dressing applications are considered. This review provides valuable information on the current status of -based hydrogels for the delivery of therapeutic agents in wound dressings and highlights their potential to improve wound healing outcomes.

Citing Articles

Exploration of natural products for the development of promising cholinesterase inhibitors in Alzheimer's disease treatment.

Nour H, Abchir O, Mounadi N, Samadi A, Salah B, Chtita S Heliyon. 2025; 11(4):e42479.

PMID: 40034281 PMC: 11874547. DOI: 10.1016/j.heliyon.2025.e42479.


Soothing the Itch: The Role of Medicinal Plants in Alleviating Pruritus in Palliative Care.

Goncalves S, Fernandes L, Caramelo A, Martins M, Rodrigues T, Matos R Plants (Basel). 2025; 13(24.

PMID: 39771213 PMC: 11677410. DOI: 10.3390/plants13243515.


Health-Related Messages About Herbs, Spices, and Other Botanicals Appearing in Print Issues and Websites of Legacy Media: Content Analysis and Evaluation.

Gaba A, Bennett R JMIR Form Res. 2024; 8:e63281.

PMID: 39631062 PMC: 11656503. DOI: 10.2196/63281.


Hydrogel for Sustained Delivery of Therapeutic Agents.

Musuc A, Mititelu M, Chelu M Gels. 2024; 10(11).

PMID: 39590073 PMC: 11593707. DOI: 10.3390/gels10110717.


Hydrogels with Essential Oils: Recent Advances in Designs and Applications.

Chelu M Gels. 2024; 10(10).

PMID: 39451288 PMC: 11508064. DOI: 10.3390/gels10100636.


References
1.
Perez-Luna V, Gonzalez-Reynoso O . Encapsulation of Biological Agents in Hydrogels for Therapeutic Applications. Gels. 2019; 4(3). PMC: 6209244. DOI: 10.3390/gels4030061. View

2.
Nair G, Naidu G, Jain S, Nagi R, Makkad R, Jha A . Clinical Effectiveness of Aloe Vera in the Management of Oral Mucosal Diseases- A Systematic Review. J Clin Diagn Res. 2016; 10(8):ZE01-7. PMC: 5028429. DOI: 10.7860/JCDR/2016/18142.8222. View

3.
Leitgeb M, Kupnik K, Knez Z, Primozic M . Enzymatic and Antimicrobial Activity of Biologically Active Samples from and . Biology (Basel). 2021; 10(8). PMC: 8389549. DOI: 10.3390/biology10080765. View

4.
Alkekhia D, LaRose C, Shukla A . β-Lactamase-Responsive Hydrogel Drug Delivery Platform for Bacteria-Triggered Cargo Release. ACS Appl Mater Interfaces. 2022; 14(24):27538-27550. DOI: 10.1021/acsami.2c02614. View

5.
Ahluwalia B, Magnusson M, Isaksson S, Larsson F, Ohman L . Effects of Aloe barbadensis Mill. extract (AVH200®) on human blood T cell activity in vitro. J Ethnopharmacol. 2016; 179:301-9. DOI: 10.1016/j.jep.2016.01.003. View