[Nocturnal Blood Pressure Fluctuations in Obstructive Sleep Apnea-Hypopnea Syndrome]

Overview

Journal Open Respir Arch

Specialty Pulmonary Medicine

Date 2023 Jul 27

PMID 37497359

Authors

Maria Jesus Pablo Zaro

Isabel Benavente Aguilar

Yolanda Lasierra Periz

Fernanda Romero Puertas

Virginia Majarenas Mascunano

Jose Carlos Sanjuan Abian

Luis Borderias Clau

Elena Briz Munoz

Affiliations

Soon will be listed here.

Abstract

Objective: Patients with sleep apnea/hypopnea syndrome and episodes of increased systolic pressure during sleep, with and without arterial hypertension, and HT as a marker of increased cardiovascular risk, were studied in a prospective study. The objective of our study was to demonstrate that patients with increased systolic pressure during sleep who also had arterial hypertension had a higher cardiovascular risk than non-hypertensive patients.

Methods: We analyzed various biometric (muscle mass index, baseline blood pressure) and polysomnographic parameters, including AHI (apnea-hypopnea index/hour), O2 desaturation index/hour, arousal index, baseline and minimum O2 saturation and the proportion of different sleep phases, together with comorbidities and associated treatments in patients with sleep apnea/hypopnea syndrome (64 with arterial hypertension and 38 non-hypertensive patients) with episodes of increased systolic blood pressure during sleep during polysomnographic studies conducted between 2013 and 2017 and in 2020.

Results: There were no statistically significant differences in the different parameters between study groups. Patients in both groups developed comorbidities in the follow-up period, more frequently in the hypertensive group, and required new treatments, especially the group of patients with HT.

Conclusion: Episodes of increased systolic pressure during sleep suggest an increased cardiovascular risk in patients with sleep apnea syndrome and arterial hypertension in terms of associated comorbidities. However, in non-hypertensive patients, episodes of increased systolic pressure may also be associated with a higher risk of vascular comorbidities (higher than the risk associated with isolated obstructive sleep apneas).

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