Recent Updates in Autonomic Research: Orthostatic Hypotension and Cognitive Function in Parkinson Disease and Multiple System Atrophy, the Skin As a Window into Synuclein Pathology, and RFC1 Repeat Expansions in Hereditary Sensory Autonomic...

Overview

Journal Clin Auton Res

Date 2023 Jul 26

PMID 37493897

Authors

Pitcha Chompoopong

Sandra Reiter-Campeau

Affiliations

Soon will be listed here.

References

Centi J, Freeman R, Gibbons C, Neargarder S, Canova A, Cronin-Golomb A . Effects of orthostatic hypotension on cognition in Parkinson disease. Neurology. 2016; 88(1):17-24. PMC: 5200856. DOI: 10.1212/WNL.0000000000003452. View

Ou Y, Tan C, Shen X, Xu W, Hou X, Dong Q . Blood Pressure and Risks of Cognitive Impairment and Dementia: A Systematic Review and Meta-Analysis of 209 Prospective Studies. Hypertension. 2020; 76(1):217-225. DOI: 10.1161/HYPERTENSIONAHA.120.14993. View

Xia X, Wang R, Vetrano D, Grande G, Laukka E, Ding M . From Normal Cognition to Cognitive Impairment and Dementia: Impact of Orthostatic Hypotension. Hypertension. 2021; 78(3):769-778. PMC: 8357050. DOI: 10.1161/HYPERTENSIONAHA.121.17454. View

Velseboer D, de Haan R, Wieling W, Goldstein D, de Bie R . Prevalence of orthostatic hypotension in Parkinson's disease: a systematic review and meta-analysis. Parkinsonism Relat Disord. 2011; 17(10):724-9. PMC: 5199613. DOI: 10.1016/j.parkreldis.2011.04.016. View

Wenning G, Shlomo Y, Magalhaes M, Daniel S, Quinn N . Clinical features and natural history of multiple system atrophy. An analysis of 100 cases. Brain. 1994; 117 ( Pt 4):835-45. DOI: 10.1093/brain/117.4.835. View

Ruiz Barrio I, Miki Y, Jaunmuktane Z, Warner T, De Pablo-Fernandez E . Association Between Orthostatic Hypotension and Dementia in Patients With Parkinson Disease and Multiple System Atrophy. Neurology. 2022; 100(10):e998-e1008. PMC: 9990860. DOI: 10.1212/WNL.0000000000201659. View

Loureiro D, Bilbao R, Bordet S, Grasso L, Otero-Losada M, Capani F . A systematic review and meta-analysis on the association between orthostatic hypotension and mild cognitive impairment and dementia in Parkinson's disease. Neurol Sci. 2022; 44(4):1211-1222. DOI: 10.1007/s10072-022-06537-3. View

McDonald C, Newton J, Burn D . Orthostatic hypotension and cognitive impairment in Parkinson's disease: Causation or association?. Mov Disord. 2016; 31(7):937-46. DOI: 10.1002/mds.26632. View

Udow S, Robertson A, MacIntosh B, Espay A, Rowe J, Lang A . 'Under pressure': is there a link between orthostatic hypotension and cognitive impairment in α-synucleinopathies?. J Neurol Neurosurg Psychiatry. 2016; 87(12):1311-1321. DOI: 10.1136/jnnp-2016-314123. View

10.

Donadio V . Skin nerve α-synuclein deposits in Parkinson's disease and other synucleinopathies: a review. Clin Auton Res. 2018; 29(6):577-585. DOI: 10.1007/s10286-018-0581-4. View

11.

Gibbons C, Wang N, Rajan S, Kern D, Palma J, Kaufmann H . Cutaneous α-Synuclein Signatures in Patients With Multiple System Atrophy and Parkinson Disease. Neurology. 2023; 100(15):e1529-e1539. PMC: 10103107. DOI: 10.1212/WNL.0000000000206772. View

12.

Adler C, Beach T, Hentz J, Shill H, Caviness J, Driver-Dunckley E . Low clinical diagnostic accuracy of early vs advanced Parkinson disease: clinicopathologic study. Neurology. 2014; 83(5):406-12. PMC: 4132570. DOI: 10.1212/WNL.0000000000000641. View

13.

Gibbons C, Freeman R, Bellaire B, Adler C, Moore D, Levine T . Synuclein-One study: skin biopsy detection of phosphorylated α-synuclein for diagnosis of synucleinopathies. Biomark Med. 2022; 16(7):499-509. PMC: 9169016. DOI: 10.2217/bmm-2021-0646. View

14.

Rotthier A, Baets J, De Vriendt E, Jacobs A, Auer-Grumbach M, Levy N . Genes for hereditary sensory and autonomic neuropathies: a genotype-phenotype correlation. Brain. 2009; 132(Pt 10):2699-711. PMC: 2759337. DOI: 10.1093/brain/awp198. View

15.

Beijer D, Dohrn M, De Winter J, Fazal S, Cortese A, Stojkovic T . RFC1 repeat expansions: A recurrent cause of sensory and autonomic neuropathy with cough and ataxia. Eur J Neurol. 2022; 29(7):2156-2161. DOI: 10.1111/ene.15310. View

16.

Yuan J, Higuchi Y, Ando M, Matsuura E, Hashiguchi A, Yoshimura A . Multi-type repeat expansions as the most common cause of hereditary sensory and autonomic neuropathy. Front Neurol. 2022; 13:986504. PMC: 9428154. DOI: 10.3389/fneur.2022.986504. View

17.

Record C, Alnasser Alsukhni R, Curro R, Kaski D, Rubin J, Morris H . Severe distinct dysautonomia in RFC1-related disease associated with Parkinsonism. J Peripher Nerv Syst. 2022; 27(4):311-315. PMC: 10092280. DOI: 10.1111/jns.12515. View

18.

Sullivan R, Yau W, Chelban V, Rossi S, OConnor E, Wood N . RFC1 Intronic Repeat Expansions Absent in Pathologically Confirmed Multiple Systems Atrophy. Mov Disord. 2020; 35(7):1277-1279. DOI: 10.1002/mds.28074. View