Can Modified Frailty Index Predict Postoperative Complication After Lung Cancer Surgery?

Overview

Journal Gen Thorac Cardiovasc Surg

Specialties Cardiology & Vascular Diseases
General Surgery
Pulmonary Medicine

Date 2023 Jul 20

PMID 37474741

Authors

Hironobu Wada

Hidemi Suzuki

Yuichi Sakairi

Kazuhisa Tanaka

Yuki Sata

Takahide Toyoda

Terunaga Inage

Yukiko Matsui

Ichiro Yoshino

Affiliations

Soon will be listed here.

Abstract

Purpose: The impact of the modified frailty index (mFI) on postoperative complications after lung cancer surgery was investigated.

Methods: Patients who underwent lung cancer surgery in 2017 were included. 30-day postoperative mortality and morbidity were evaluated according to their Clavien-Dindo classification. mFI values are presented as the sum of values of 11 included items. Logistic regression was used to assess the effect of mFI on postoperative severe complication incidence.

Results: Among 190 patients considered, severe postoperative complications (Grade 3 or more) were observed in 30 (16%). No patients died within 30 days of surgery. The incidence of severe complications was 3.6% in patients with mFI of 0, 16.2% in patients with mFI of 1, 23.4% in patients with mFI of 2, and 31.6% in patients with mFI of 3 or more, and was correlated with the grade of mFI. Univariate and multivariate analyses showed that the high mFI was significantly predictive of postoperative complications. Frail patients of mFI ≥ 2 were at 3.0-fold greater risk of severe complications than non-frail patients of mFI 0 or 1.

Conclusion: mFI was associated with morbidity after lung cancer surgery. Preoperative frailty assessment and appropriate intervention to frail patients would be required to improve postoperative outcomes.

Citing Articles

The prognostic significance of modified frailty index-5 in patients undergoing pneumonectomy for lung cancer.

Sayan M, Artiran B, Ozturk F, Fattahov M, Akarsu I, Aslan M Interdiscip Cardiovasc Thorac Surg. 2024; 39(5).

PMID: 39475437 PMC: 11557900. DOI: 10.1093/icvts/ivae179.

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