A Systematic Analysis of Additive Manufacturing Techniques in the Bioengineering of In Vitro Cardiovascular Models

Overview

Journal Ann Biomed Eng

Specialty Biomedical Engineering

Date 2023 Jul 19

PMID 37466879

Authors

Hemanth Ponnambalath Mohanadas

Vivek Nair

Akbar Abbas Doctor

Ahmad Athif Mohd Faudzi

Nick Tucker

Ahmad Fauzi Ismail

Seeram Ramakrishna

Syafiqah Saidin

Saravana Kumar Jaganathan

Affiliations

Soon will be listed here.

Abstract

Additive Manufacturing is noted for ease of product customization and short production run cost-effectiveness. As our global population approaches 8 billion, additive manufacturing has a future in maintaining and improving average human life expectancy for the same reasons that it has advantaged general manufacturing. In recent years, additive manufacturing has been applied to tissue engineering, regenerative medicine, and drug delivery. Additive Manufacturing combined with tissue engineering and biocompatibility studies offers future opportunities for various complex cardiovascular implants and surgeries. This paper is a comprehensive overview of current technological advancements in additive manufacturing with potential for cardiovascular application. The current limitations and prospects of the technology for cardiovascular applications are explored and evaluated.

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References

Kurokawa Y, George S . Tissue engineering the cardiac microenvironment: Multicellular microphysiological systems for drug screening. Adv Drug Deliv Rev. 2015; 96:225-33. PMC: 4869857. DOI: 10.1016/j.addr.2015.07.004. View

Qiu X, Lu B, Xu N, Yan C, Ouyang W, Liu Y . [Feasibility of device closure for multiple atrial septal defects using 3D printing and ultrasound-guided intervention technique]. Zhonghua Yi Xue Za Zhi. 2017; 97(16):1214-1217. DOI: 10.3760/cma.j.issn.0376-2491.2017.16.006. View

Chepelev L, Wake N, Ryan J, Althobaity W, Gupta A, Arribas E . Radiological Society of North America (RSNA) 3D printing Special Interest Group (SIG): guidelines for medical 3D printing and appropriateness for clinical scenarios. 3D Print Med. 2019; 4(1):11. PMC: 6251945. DOI: 10.1186/s41205-018-0030-y. View

Little S, Vukicevic M, Avenatti E, Ramchandani M, Barker C . 3D Printed Modeling for Patient-Specific Mitral Valve Intervention: Repair With a Clip and a Plug. JACC Cardiovasc Interv. 2016; 9(9):973-5. DOI: 10.1016/j.jcin.2016.02.027. View

Riahi M, Velasco Forte M, Byrne N, Hermuzi A, Jones M, Baruteau A . Early experience of transcatheter correction of superior sinus venosus atrial septal defect with partial anomalous pulmonary venous drainage. EuroIntervention. 2018; 14(8):868-876. DOI: 10.4244/EIJ-D-18-00304. View

Kilian D, Ahlfeld T, Akkineni A, Bernhardt A, Gelinsky M, Lode A . 3D Bioprinting of osteochondral tissue substitutes - in vitro-chondrogenesis in multi-layered mineralized constructs. Sci Rep. 2020; 10(1):8277. PMC: 7237416. DOI: 10.1038/s41598-020-65050-9. View

Timmis A, Townsend N, Gale C, Grobbee R, Maniadakis N, Flather M . European Society of Cardiology: Cardiovascular Disease Statistics 2017. Eur Heart J. 2017; 39(7):508-579. DOI: 10.1093/eurheartj/ehx628. View

Treasure T, Petrou M, Rosendahl U, Austin C, Rega F, Pirk J . Personalized external aortic root support: a review of the current status. Eur J Cardiothorac Surg. 2016; 50(3):400-4. DOI: 10.1093/ejcts/ezw078. View

Schmauss D, Schmitz C, Bigdeli A, Weber S, Gerber N, Beiras-Fernandez A . Three-dimensional printing of models for preoperative planning and simulation of transcatheter valve replacement. Ann Thorac Surg. 2012; 93(2):e31-3. DOI: 10.1016/j.athoracsur.2011.09.031. View

10.

Tenekecioglu E, Bourantas C, Abdelghani M, Zeng Y, Silva R, Tateishi H . From drug eluting stents to bioresorbable scaffolds; to new horizons in PCI. Expert Rev Med Devices. 2016; 13(3):271-86. DOI: 10.1586/17434440.2016.1143356. View

11.

Schmauss D, Gerber N, Sodian R . Three-dimensional printing of models for surgical planning in patients with primary cardiac tumors. J Thorac Cardiovasc Surg. 2013; 145(5):1407-8. DOI: 10.1016/j.jtcvs.2012.12.030. View

12.

Biglino G, Verschueren P, Zegels R, Taylor A, Schievano S . Rapid prototyping compliant arterial phantoms for in-vitro studies and device testing. J Cardiovasc Magn Reson. 2013; 15:2. PMC: 3564729. DOI: 10.1186/1532-429X-15-2. View

13.

Schievano S, Migliavacca F, Coats L, Khambadkone S, Carminati M, Wilson N . Percutaneous pulmonary valve implantation based on rapid prototyping of right ventricular outflow tract and pulmonary trunk from MR data. Radiology. 2007; 242(2):490-7. DOI: 10.1148/radiol.2422051994. View

14.

Itagaki M . Using 3D printed models for planning and guidance during endovascular intervention: a technical advance. Diagn Interv Radiol. 2015; 21(4):338-41. PMC: 4498430. DOI: 10.5152/dir.2015.14469. View

15.

Ginty O, Moore J, Eskandari M, Carnahan P, Lasso A, Jolley M . Dynamic, patient-specific mitral valve modelling for planning transcatheter repairs. Int J Comput Assist Radiol Surg. 2019; 14(7):1227-1235. DOI: 10.1007/s11548-019-01998-y. View

16.

Fathi P, Capron G, Tripathi I, Misra S, Ostadhossein F, Selmic L . Computed tomography-guided additive manufacturing of Personalized Absorbable Gastrointestinal Stents for intestinal fistulae and perforations. Biomaterials. 2019; 228:119542. PMC: 7982053. DOI: 10.1016/j.biomaterials.2019.119542. View

17.

Fujita B, Kutting M, Seiffert M, Scholtz S, Egron S, Prashovikj E . Calcium distribution patterns of the aortic valve as a risk factor for the need of permanent pacemaker implantation after transcatheter aortic valve implantation. Eur Heart J Cardiovasc Imaging. 2016; 17(12):1385-1393. DOI: 10.1093/ehjci/jev343. View

18.

Farooqi K, Gonzalez-Lengua C, Shenoy R, Sanz J, Nguyen K . Use of a Three Dimensional Printed Cardiac Model to Assess Suitability for Biventricular Repair. World J Pediatr Congenit Heart Surg. 2016; 7(3):414-6. DOI: 10.1177/2150135115610285. View

19.

Kappanayil M, Koneti N, Kannan R, Kottayil B, Kumar K . Three-dimensional-printed cardiac prototypes aid surgical decision-making and preoperative planning in selected cases of complex congenital heart diseases: Early experience and proof of concept in a resource-limited environment. Ann Pediatr Cardiol. 2017; 10(2):117-125. PMC: 5431022. DOI: 10.4103/apc.APC_149_16. View

20.

Vukicevic M, Mosadegh B, Min J, Little S . Cardiac 3D Printing and its Future Directions. JACC Cardiovasc Imaging. 2017; 10(2):171-184. PMC: 5664227. DOI: 10.1016/j.jcmg.2016.12.001. View