The Crucial Findings Derived from the Special Issue "Inside Cancer Genomics: From Structure to Therapy"
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Abstract
Cancer initiation, growth, and progression are sustained by multiple types of genetic alterations, ranging in size from single point mutations, focal genomic errors to broad chromosomal copy number alterations, gains, and losses [...].
References
1.
Barresi V, Di Bella V, Lo Nigro L, Privitera A, Bonaccorso P, Scuderi C
. Temporary serine protease inhibition and the role of SPINK2 in human bone marrow. iScience. 2023; 26(6):106949.
PMC: 10291479.
DOI: 10.1016/j.isci.2023.106949.
View
2.
Davoli T, Uno H, Wooten E, Elledge S
. Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy. Science. 2017; 355(6322).
PMC: 5592794.
DOI: 10.1126/science.aaf8399.
View
3.
. Pan-cancer analysis of whole genomes. Nature. 2020; 578(7793):82-93.
PMC: 7025898.
DOI: 10.1038/s41586-020-1969-6.
View
4.
Wong J, Aichmuller C, Schulze M, Hlevnjak M, Elgaafary S, Lichter P
. Association of mutation signature effectuating processes with mutation hotspots in driver genes and non-coding regions. Nat Commun. 2022; 13(1):178.
PMC: 8748499.
DOI: 10.1038/s41467-021-27792-6.
View
5.
Rubinstein T, Reuveni I, Hesin A, Klein-Goldberg A, Olauson H, Larsson T
. A Transgenic Model Reveals the Role of Klotho in Pancreatic Cancer Development and Paves the Way for New Klotho-Based Therapy. Cancers (Basel). 2021; 13(24).
PMC: 8699737.
DOI: 10.3390/cancers13246297.
View