Physiologic Markers of Disease Severity in ARDS

Overview

Journal Respir Care

Publisher Mary Ann Liebert

Specialty Pulmonary Medicine

Date 2023 Jul 12

PMID 37438051

Authors

Joao F F M Ferraz

Matthew T Siuba

Sudhir Krishnan

Robert L Chatburn

Eduardo Mireles-Cabodevila

Abhijit Duggal

Affiliations

Soon will be listed here.

Abstract

Despite its significant limitations, the P /F remains the standard tool to classify disease severity in ARDS. Treatment decisions and research enrollment have depended on this parameter for over 50 years. In addition, several variables have been studied over the past few decades, incorporating other physiologic considerations such as ventilation efficiency, lung mechanics, and right-ventricular performance. This review describes the strengths and limitations of all relevant parameters, with the goal of helping us better understand disease severity and possible future treatment targets.

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