N-terminal Sequence Homologies in Interstitial Retinol-binding Proteins from 10 Vertebrate Species

Overview

Journal FEBS Lett

Specialty Biochemistry

Date 1986 Sep 15

PMID 3743780

Citations 3

Authors

S L Fong

R G Cook

R A Alvarez

G I Liou

R A Landers

C D Bridges

Affiliations

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Abstract

We report here the first comprehensive comparative NH2-terminal sequence studies of interstitial retinol-binding protein (IRBPs) from nine mammals (including cattle) and one amphibian. This study has revealed that in many species the N-terminus of IRBP includes a 3-6 amino acid extension. IRBP possessing this leader sequence is sometimes mixed with IRBP from which this sequence has been excised.

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Goldfish cones secrete a two-repeat interphotoreceptor retinoid-binding protein.

Wagenhorst B, Rajendran R, Van Niel E, Hessler R, Bukelman A, Gonzalez-Fernandez F J Mol Evol. 1995; 41(5):646-56.

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