Paragangliomas of the Head and Neck: a Contemporary Review

Overview

Journal Endocr Oncol

Date 2023 Jul 12

PMID 37435464

Authors

Nathan J Graham

Joshua D Smith

Tobias Else

Gregory J Basura

Affiliations

Soon will be listed here.

Abstract

Head and neck paragangliomas (HNPGLs) are slow-growing, vascular, typically benign tumors whose growth may induce significant lower cranial nerve deficits. While most tumors arise sporadically, a significant portion is associated with defined genetic syndromes. While surgical resection has historically been the gold standard, management strategies have evolved with acknowledgement of high surgical morbidity, slow tumor growth rates, and technological advances. Conservative management approaches via observation and newer radiation therapy techniques have become more common. This review seeks to provide an update on contemporary management strategies for HNPGLs and future directions.

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