GeCoNet-Tool: a Software Package for Gene Co-expression Network Construction and Analysis

Overview

Journal BMC Bioinformatics

Publisher Biomed Central

Specialty Biology

Date 2023 Jul 11

PMID 37434115

Authors

Junyao Kuang

Kristin Michel

Caterina Scoglio

Affiliations

Soon will be listed here.

Abstract

Background: Network analysis is a powerful tool for studying gene regulation and identifying biological processes associated with gene function. However, constructing gene co-expression networks can be a challenging task, particularly when dealing with a large number of missing values.

Results: We introduce GeCoNet-Tool, an integrated gene co-expression network construction and analysis tool. The tool comprises two main parts: network construction and network analysis. In the network construction part, GeCoNet-Tool offers users various options for processing gene co-expression data derived from diverse technologies. The output of the tool is an edge list with the option of weights associated with each link. In network analysis part, the user can produce a table that includes several network properties such as communities, cores, and centrality measures. With GeCoNet-Tool, users can explore and gain insights into the complex interactions between genes.

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