Structural Basis of Ligand Activation and Inhibition in a Mammalian TRPV4 Ion Channel
Overview
Affiliations
Structure- and Ligand-Based Virtual Screening for Identification of Novel TRPV4 Antagonists.
Saadabadi A, Wilkman L, Rantanen M, Koivisto A, Salo-Ahen O Molecules. 2025; 30(1.
PMID: 39795157 PMC: 11722135. DOI: 10.3390/molecules30010100.
Forty sites of TRP channel regulation.
Talyzina I, Nadezhdin K, Sobolevsky A Curr Opin Chem Biol. 2024; 84:102550.
PMID: 39615427 PMC: 11788071. DOI: 10.1016/j.cbpa.2024.102550.
TRPV4 Channel in Neurological Disease: from Molecular Mechanisms to Therapeutic Potential.
Zhang F, Mehta H, Choudhary H, Islam R, Hanafy K Mol Neurobiol. 2024; 62(3):3877-3891.
PMID: 39333347 PMC: 11790740. DOI: 10.1007/s12035-024-04518-5.
Structural Pharmacology of TRPV4 Antagonists.
Fan J, Guo C, Liao D, Ke H, Lei J, Xie W Adv Sci (Weinh). 2024; 11(25):e2401583.
PMID: 38659239 PMC: 11220649. DOI: 10.1002/advs.202401583.
Piezo channels in the intestinal tract.
He H, Zhou J, Xu X, Zhou P, Zhong H, Liu M Front Physiol. 2024; 15:1356317.
PMID: 38379701 PMC: 10877011. DOI: 10.3389/fphys.2024.1356317.