» Articles » PMID: 37426698

A Primer on Common Supplements and Dietary Measures Used by Patients with Inflammatory Bowel Disease

Overview
Publisher Sage Publications
Date 2023 Jul 10
PMID 37426698
Authors
Affiliations
Soon will be listed here.
Abstract

Inflammatory bowel disease (IBD) is a chronic disease of the intestines. The pathophysiology of IBD, namely Crohn's disease and ulcerative colitis, is a complex interplay between environmental, genetic, and immune factors. Physicians and patients often seek complementary and alternative medicines (CAMs) as primary and supplementary treatment modalities. CAMs in IBD span a wide range of plants, herbs, pre/probiotics, and include formulations, such as cannabis, curcumin, fish oil, and De Simone Formulation. Dietary measures are also used to improve symptoms by attempting to target trigger foods and reducing inflammation. Examples include the specific carbohydrate diet, the Mediterranean diet, and a diet low in fermentable oligo-, di- and monosaccharides as well as polyols (FODMAP). We examine and review the most common complementary supplements and diets used by patients with IBD.

Citing Articles

Key Focus Areas in Pouchitis Therapeutic Status: A Narrative Review.

Hosseini-Asl S, Mehrabani G, Masoumi S Iran J Med Sci. 2024; 49(8):472-486.

PMID: 39205822 PMC: 11347594. DOI: 10.30476/ijms.2024.100782.3326.


Potential Diagnostic Role of Hepcidin in Anemic Patients Affected by Inflammatory Bowel Disease: A Systematic Review.

Ferrari F, Carini M, Zanella I, Treglia G, Luglio G, Bresciani R Diagnostics (Basel). 2024; 14(4).

PMID: 38396414 PMC: 10887700. DOI: 10.3390/diagnostics14040375.

References
1.
Yanai H, Levine A, Hirsch A, Sigall Boneh R, Kopylov U, Eran H . The Crohn's disease exclusion diet for induction and maintenance of remission in adults with mild-to-moderate Crohn's disease (CDED-AD): an open-label, pilot, randomised trial. Lancet Gastroenterol Hepatol. 2021; 7(1):49-59. DOI: 10.1016/S2468-1253(21)00299-5. View

2.
Sandborn W, Targan S, Byers V, Rutty D, Mu H, Zhang X . Andrographis paniculata extract (HMPL-004) for active ulcerative colitis. Am J Gastroenterol. 2012; 108(1):90-8. PMC: 3538174. DOI: 10.1038/ajg.2012.340. View

3.
Naganuma M, Sugimoto S, Fukuda T, Mitsuyama K, Kobayashi T, Yoshimura N . Indigo naturalis is effective even in treatment-refractory patients with ulcerative colitis: a post hoc analysis from the INDIGO study. J Gastroenterol. 2019; 55(2):169-180. DOI: 10.1007/s00535-019-01625-2. View

4.
Grammatikopoulou M, Goulis D, Gkiouras K, Nigdelis M, Papageorgiou S, Papamitsou T . Low FODMAP Diet for Functional Gastrointestinal Symptoms in Quiescent Inflammatory Bowel Disease: A Systematic Review of Randomized Controlled Trials. Nutrients. 2020; 12(12). PMC: 7760970. DOI: 10.3390/nu12123648. View

5.
Park M, Kwon H, Sung M . Dietary aloin, aloesin, or aloe-gel exerts anti-inflammatory activity in a rat colitis model. Life Sci. 2011; 88(11-12):486-92. DOI: 10.1016/j.lfs.2011.01.010. View