B-mode Shear Wave Elastography Can Be an Alternative Method to Vibration-controlled Transient Elastography According to a Moderate-scale Population Study

Overview

Journal J Med Ultrason (2001)

Specialty Radiology

Date 2023 Jul 4

PMID 37402022

Authors

Masashi Hirooka

Yohei Koizumi

Yoshiko Nakamura

Ryo Yano

Kana Hirooka

Makoto Morita

Yusuke Imai

Yoshio Tokumoto

Masanori Abe

Yoichi Hiasa

Affiliations

Soon will be listed here.

Abstract

Purpose: We aimed to compare vibration-controlled transient elastography (VCTE) with shear wave elastography (SWE) without previous analysis and generate regression equations between VCTE and new point SWE using combination-elastography.

Methods: Overall, 829 patients with chronic liver disease were enrolled in this study. Patients with a skin-liver capsule distance > 25 mm were excluded. The reproducibility of VCTE and SWE was confirmed in a phantom study and a clinical study. Considering that combination-elastography allows measurement based on strain elastography, a similar analysis was performed for the liver fibrosis index (LFI), which is a quantitative value for evaluation of liver fibrosis calculated using strain elastography image features. Regression equations between the VCTE and SWE values were obtained based on linear regression analysis.

Results: In the phantom study and clinical study, there was a strong correlation between VCTE and SWE [r = 0.995 (p < 0.001) and r = 0.747 (p < 0.001), respectively). The regression equation between VCTE and SWE was VCTE (kPa) = 1.09 × point SWE (kPa) - 0.17. The Bland-Altman plots revealed no statistically significant bias. Meanwhile, there was no correlation between VCTE and LFI (r = 0.279). There was a statistically significant bias between VCTE and LFI in the Bland-Altman plots. The inter-operator reliability showed a good intraclass correlation coefficient of 0.760 (95% confidence interval: 0.720-0.779).

Conclusion: Liver stiffness measured using point SWE was comparable to that measured using VCTE.

Citing Articles

iATT liver fat quantification for steatosis grading by referring to MRI proton density fat fraction: a multicenter study.

Hirooka M, Ogawa S, Koizumi Y, Yoshida Y, Goto T, Yasuda S J Gastroenterol. 2024; 59(6):504-514.

PMID: 38553657 PMC: 11128405. DOI: 10.1007/s00535-024-02096-w.

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