Approaches to Neuroprotection in Pediatric Neurocritical Care

Overview

Journal World J Crit Care Med

Publisher Baishideng Publishing Group

Specialty Critical Care

Date 2023 Jul 3

PMID 37397588

Authors

Angad Kochar

Kara Hildebrandt

Rebecca Silverstein

Brian Appavu

Affiliations

Soon will be listed here.

Abstract

Acute neurologic injuries represent a common cause of morbidity and mortality in children presenting to the pediatric intensive care unit. After primary neurologic insults, there may be cerebral brain tissue that remains at risk of secondary insults, which can lead to worsening neurologic injury and unfavorable outcomes. A fundamental goal of pediatric neurocritical care is to mitigate the impact of secondary neurologic injury and improve neurologic outcomes for critically ill children. This review describes the physiologic framework by which strategies in pediatric neurocritical care are designed to reduce the impact of secondary brain injury and improve functional outcomes. Here, we present current and emerging strategies for optimizing neuroprotective strategies in critically ill children.

Citing Articles

Neuromonitoring in Pediatric Neurocritical Care: An Introduction.

Appavu B, Kirschen M, Bell M Neurocrit Care. 2024; 41(1):17-19.

PMID: 38689192 DOI: 10.1007/s12028-024-01988-2.

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