» Articles » PMID: 37389093

Food Allergy Prevention: Where Are We in 2023?

Overview
Publisher Wolters Kluwer
Date 2023 Jun 30
PMID 37389093
Authors
Affiliations
Soon will be listed here.
Abstract

Food allergy prevention involves recommendations to the maternal diet during pregnancy and breast feeding, early life feeding and introduction of solid foods. Pregnant and breastfeeding women are not recommended to exclude any food allergens from their diet, but data are lacking to support active consumption of food allergens for prevention of food allergy. Breastfeeding is recommended for the many health benefits to the mother and child but has not shown any association with reduction in childhood food allergies. There is currently no recommendation regarding the use of any infant formula for allergy prevention, including the use of partially or extensively hydrolyzed formulas. Once the introduction of solid food commences, based on randomized controlled trials, it is advised to actively introduce peanuts and egg early into the infant diet and continue with consumption of these. Although there are limited data with respect to other major food allergens and whether early introduction may prevent allergy development, there is no need to delay the introduction of these allergens into the infant diet. Interpreting food allergen consumption in the context of cultural food practices has not been studied, but it makes sense to introduce the infant to family foods by 1 year of age. Consumption of foods typical of the Western diet and foods high in advanced glycation end products may be associated with an increase in food allergies. Similarly, intake of micronutrients, such as vitamin D and omega-3 fatty acids in both the maternal and infant diet, needs further clarification in the context of food allergy prevention.

Citing Articles

Diversity of complementary diet and early food allergy risk.

Boden S, Lindam A, Venter C, Ulfsdotter R, Domellof M, West C Pediatr Allergy Immunol. 2025; 36(1):e70035.

PMID: 39868464 PMC: 11771557. DOI: 10.1111/pai.70035.


Efficient Hydrolysis of Fish Parvalbumin by Marine Bacterial Protease VSP2V-280: Allergen Removal.

Zhou J, Bai Y, Gao Y, Tian H, Wang M, Kang X Food Sci Nutr. 2025; 13(1):e4729.

PMID: 39803265 PMC: 11717067. DOI: 10.1002/fsn3.4729.


The evolution of nutritional care in children with food allergies - With a focus on cow's milk allergy.

Meyer R, Groetch M, Santos A, Venter C J Hum Nutr Diet. 2024; 38(1):e13391.

PMID: 39587736 PMC: 11589409. DOI: 10.1111/jhn.13391.


Differences in the Course, Diagnosis, and Treatment of Food Allergies Depending on Age-Comparison of Children and Adults.

Kuzniar J, Kozubek P, Gomulka K Nutrients. 2024; 16(9).

PMID: 38732564 PMC: 11085589. DOI: 10.3390/nu16091317.


Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy Prevention.

Manti S, Galletta F, Bencivenga C, Bettini I, Klain A, DAddio E Nutrients. 2024; 16(7).

PMID: 38613120 PMC: 11013058. DOI: 10.3390/nu16071087.


References
1.
Moonesinghe H, Patil V, Dean T, Arshad S, Glasbey G, Grundy J . Association between healthy eating in pregnancy and allergic status of the offspring in childhood. Ann Allergy Asthma Immunol. 2015; 116(2):163-5. DOI: 10.1016/j.anai.2015.11.005. View

2.
Goldring S, Griffiths C, Martineau A, Robinson S, Yu C, Poulton S . Prenatal vitamin d supplementation and child respiratory health: a randomised controlled trial. PLoS One. 2013; 8(6):e66627. PMC: 3691177. DOI: 10.1371/journal.pone.0066627. View

3.
Vahdaninia M, Mackenzie H, Dean T, Helps S . ω-3 LCPUFA supplementation during pregnancy and risk of allergic outcomes or sensitization in offspring: A systematic review and meta-analysis. Ann Allergy Asthma Immunol. 2018; 122(3):302-313.e2. DOI: 10.1016/j.anai.2018.12.008. View

4.
Smith P . Do advanced glycation end-products cause food allergy?. Curr Opin Allergy Clin Immunol. 2017; 17(5):325-331. DOI: 10.1097/ACI.0000000000000385. View

5.
Clausen M, Jonasson K, Keil T, Beyer K, Sigurdardottir S . Fish oil in infancy protects against food allergy in Iceland-Results from a birth cohort study. Allergy. 2018; 73(6):1305-1312. PMC: 6032905. DOI: 10.1111/all.13385. View