Disinfection of the Air and Surfaces in the Dental Clinic Using Hydroxyl Radical (OH-) Based Technology: A Systematic Review

Overview

Journal J Clin Exp Dent

Specialty Dentistry

Date 2023 Jun 30

PMID 37388429

Authors

Anais Panos-Crespo

Bassel Traboulsi-Garet

Maria-Angeles Sanchez-Garces

Cosme Gay-Escoda

Affiliations

Soon will be listed here.

Abstract

Background: A systematic review was carried out to compare the disinfectant capacity of hydroxyl radicals (OH-) versus other products commonly used for disinfecting the air and surfaces.

Material And Methods: A literature search was made of the Cochrane Library, PubMed (MEDLINE) and Scopus databases. "In vitro" studies evaluating disinfection methods applicable to several surfaces and room air were included in the search. The search was carried out in April 2022, with no restrictions in terms of language or publication date.

Results: Of the 308 articles identified from the initial search, 8 were included for the quantitative analysis. All publications corresponded to experimental "in vitro" studies. Seven of them evaluated biocidal action against bacteria, and only two assessed activity against viral loads. The generation of contaminants secondary to application of the disinfectants was only analyzed in one of the studies, with the conclusion that the production of peroxyl radicals (RO2) derived from the oxidation of volatile organic compounds (VOCs) is greater when chemical surface disinfectants are used versus air disinfection systems.

Conclusions: The disinfection capacities of the currently available methods are similar, and none of them are able to replace the use of additional physical protection measures. Disinfection methods, hydroxyl radical, environment, surfaces, dentistry.

Citing Articles

Current Challenges in Environmental Decontamination and Instrument Reprocessing.

Walsh L Int Dent J. 2024; 74 Suppl 2:S455-S462.

PMID: 39515933 PMC: 11583872. DOI: 10.1016/j.identj.2024.08.016.

Efficacy of music therapy on stress and anxiety prior to dental treatment: a systematic review and meta-analysis of randomized clinical trials.

Lopez-Valverde N, Lopez-Valverde A, Macedo de Sousa B, Blanco Rueda J Front Psychiatry. 2024; 15:1352817.

PMID: 38463434 PMC: 10920280. DOI: 10.3389/fpsyt.2024.1352817.

References

Matsuda J, Grinbaum R, Davidowicz H . The assessment of infection control in dental practices in the municipality of São Paulo. Braz J Infect Dis. 2011; 15(1):45-51. View

Saccucci M, Ierardo G, Protano C, Vitali M, Polimeni A . How to manage the biological risk in a dental clinic: current and future perspectives. Minerva Stomatol. 2017; 66(5):232-239. DOI: 10.23736/S0026-4970.17.04087-0. View

Burton D . Using the NIOSH Pocket Guide to Chemical Hazards. Occup Health Saf. 2001; 70(4):20, 22. View

Kanno T, Nakamura K, Ikai H, Kikuchi K, Sasaki K, Niwano Y . Literature review of the role of hydroxyl radicals in chemically-induced mutagenicity and carcinogenicity for the risk assessment of a disinfection system utilizing photolysis of hydrogen peroxide. J Clin Biochem Nutr. 2012; 51(1):9-14. PMC: 3391867. DOI: 10.3164/jcbn.11-105. View

Cumbo E, Gallina G, Messina P, Scardina G . Alternative Methods of Sterilization in Dental Practices Against COVID-19. Int J Environ Res Public Health. 2020; 17(16). PMC: 7459510. DOI: 10.3390/ijerph17165736. View

Veliz E, Vergara T, Pearcy M, Dabanch J . [Importance of cleaning and disinfection of critical surfaces in dental health services. Impact of an intervention program]. Rev Chilena Infectol. 2018; 35(1):88-90. DOI: 10.4067/s0716-10182018000100088. View

Lewis D, Boe R . Cross-infection risks associated with current procedures for using high-speed dental handpieces. J Clin Microbiol. 1992; 30(2):401-6. PMC: 265068. DOI: 10.1128/jcm.30.2.401-406.1992. View

Nagraj S, Eachempati P, Paisi M, Nasser M, Sivaramakrishnan G, Verbeek J . Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious diseases. Cochrane Database Syst Rev. 2020; 10:CD013686. PMC: 8164845. DOI: 10.1002/14651858.CD013686.pub2. View

Guida M, Galle F, Di Onofrio V, Nastro R, Battista M, Liguori R . Environmental microbial contamination in dental setting: a local experience. J Prev Med Hyg. 2013; 53(4):207-12. View

10.

Yamaguchi M, Abe H, Ma T, Tadaki D, Hirano-Iwata A, Kanetaka H . Bactericidal Activity of TiO Nanotube Thin Films on Si by Photocatalytic Generation of Active Oxygen Species. Langmuir. 2020; 36(42):12668-12677. DOI: 10.1021/acs.langmuir.0c02225. View

11.

Wong V, Staniforth K, Boswell T . Environmental contamination and airborne microbial counts: a role for hydroxyl radical disinfection units?. J Hosp Infect. 2011; 78(3):194-9. DOI: 10.1016/j.jhin.2011.03.003. View

12.

Moccia G, Motta O, Pironti C, Proto A, Capunzo M, De Caro F . An alternative approach for the decontamination of hospital settings. J Infect Public Health. 2020; 13(12):2038-2044. PMC: 7577675. DOI: 10.1016/j.jiph.2020.09.020. View

13.

Mupparapu M, Kothari K . Review of surface disinfection protocols in dentistry: a 2019 update. Quintessence Int. 2019; 50(1):58-65. DOI: 10.3290/j.qi.a41337. View

14.

Riddell S, Goldie S, Hill A, Eagles D, Drew T . The effect of temperature on persistence of SARS-CoV-2 on common surfaces. Virol J. 2020; 17(1):145. PMC: 7538848. DOI: 10.1186/s12985-020-01418-7. View

15.

Araujo M, Andreana S . Risk and prevention of transmission of infectious diseases in dentistry. Quintessence Int. 2002; 33(5):376-82. View

16.

Robertson C, Clarkson J, Aceves-Martins M, Ramsay C, Richards D, Colloc T . A Review of Aerosol Generation Mitigation in International Dental Guidance. Int Dent J. 2021; 72(2):203-210. PMC: 8172569. DOI: 10.1016/j.identj.2021.04.002. View

17.

Moher D, Liberati A, Tetzlaff J, Altman D . Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg. 2010; 8(5):336-41. DOI: 10.1016/j.ijsu.2010.02.007. View

18.

Stephens J, Kiger R, Kettering J . In vitro comparison of the effectiveness of three surface disinfectants. J Calif Dent Assoc. 1994; 22(6):40-2, 44-6. View

19.

Alvarenga M, Mamede Veloso S, Bezerra A, Trindade B, Gomes A, de Melo Monteiro G . COVID-19 outbreak: Should dental and medical practices consider uv-c technology to enhance disinfection on surfaces? - A systematic review. J Photochem Photobiol. 2021; 9:100096. PMC: 8674638. DOI: 10.1016/j.jpap.2021.100096. View

20.

Marchesi I, Sala A, Frezza G, Paduano S, Turchi S, Bargellini A . virucidal efficacy of a dry steam disinfection system against Human Coronavirus, Human Influenza Virus, and Echovirus. J Occup Environ Hyg. 2021; 18(12):541-546. DOI: 10.1080/15459624.2021.1989442. View