Polymorphism of Genes and Their Impact on Beef Quality

Overview

Journal Curr Issues Mol Biol

Publisher MDPI

Specialty Molecular Biology

Date 2023 Jun 27

PMID 37367051

Authors

Piotr Kostusiak

Jan Slosarz

Marcin Golebiewski

Grzegorz Grodkowski

Kamila Puppel

Affiliations

Soon will be listed here.

Abstract

The single-nucleotide polymorphism (SNP) form of genes is a valuable source of information regarding their suitability for use as specific markers of desirable traits in beef cattle breeding. For several decades, breeding work focused on improving production efficiency through optimizing the feed conversion ratio and improving daily gains and meat quality. Many research teams previously undertook research work on single-nucleotide polymorphism in myostatin (MSTN), thyroglobulin (TG), calpain (CAPN), and calpastatin (CAST) proteins. The literature review focuses on the most frequently addressed issues concerning these genes in beef cattle production and points to a number of relevant studies on the genes' polymorphic forms. The four genes presented are worth considering during breeding work as a set of genes that can positively influence productivity and production quality.

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References

Van Der Spek A, Fliers E, Boelen A . The classic pathways of thyroid hormone metabolism. Mol Cell Endocrinol. 2017; 458:29-38. DOI: 10.1016/j.mce.2017.01.025. View

Frank D, Ball A, Hughes J, Krishnamurthy R, Piyasiri U, Stark J . Sensory and Flavor Chemistry Characteristics of Australian Beef: Influence of Intramuscular Fat, Feed, and Breed. J Agric Food Chem. 2016; 64(21):4299-311. DOI: 10.1021/acs.jafc.6b00160. View

Farmer L, Farrell D . Review: Beef-eating quality: a European journey. Animal. 2018; 12(11):2424-2433. DOI: 10.1017/S1751731118001672. View

Casas E, White S, Wheeler T, Shackelford S, Koohmaraie M, Riley D . Effects of calpastatin and micro-calpain markers in beef cattle on tenderness traits. J Anim Sci. 2006; 84(3):520-5. DOI: 10.2527/2006.843520x. View

Koohmaraie M . Effect of pH, temperature, and inhibitors on autolysis and catalytic activity of bovine skeletal muscle mu-calpain. J Anim Sci. 1992; 70(10):3071-80. DOI: 10.2527/1992.70103071x. View

Kantono K, Hamid N, Ma Q, Chadha D, Oey I . Consumers' perception and purchase behaviour of meat in China. Meat Sci. 2021; 179:108548. DOI: 10.1016/j.meatsci.2021.108548. View

Sharma M, Kambadur R, Matthews K, Somers W, Devlin G, Conaglen J . Myostatin, a transforming growth factor-beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct. J Cell Physiol. 1999; 180(1):1-9. DOI: 10.1002/(SICI)1097-4652(199907)180:1<1::AID-JCP1>3.0.CO;2-V. View

McPherron A, Lawler A, Lee S . Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature. 1997; 387(6628):83-90. DOI: 10.1038/387083a0. View

Grobet L, Martin L, Poncelet D, Pirottin D, Brouwers B, Riquet J . A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nat Genet. 1997; 17(1):71-4. DOI: 10.1038/ng0997-71. View

10.

Bouyer C, Forestier L, Renand G, Oulmouden A . Deep intronic mutation and pseudo exon activation as a novel muscular hypertrophy modifier in cattle. PLoS One. 2014; 9(5):e97399. PMC: 4020855. DOI: 10.1371/journal.pone.0097399. View

11.

Kang N, Panzone L, Kuznesof S . The role of cooking in consumers' quality formation: An exploratory study of beef steaks. Meat Sci. 2022; 186:108730. DOI: 10.1016/j.meatsci.2021.108730. View

12.

Lee J, Kim D, Lee K . Muscle Hyperplasia in Japanese Quail by Single Amino Acid Deletion in MSTN Propeptide. Int J Mol Sci. 2020; 21(4). PMC: 7073117. DOI: 10.3390/ijms21041504. View

13.

Tait Jr R, Shackelford S, Wheeler T, King D, Keele J, Casas E . CAPN1, CAST, and DGAT1 genetic effects on preweaning performance, carcass quality traits, and residual variance of tenderness in a beef cattle population selected for haplotype and allele equalization. J Anim Sci. 2014; 92(12):5382-93. DOI: 10.2527/jas.2014-8211. View

14.

Lopes F, Magnabosco C, Passafaro T, Brunes L, Costa M, Eifert E . Improving genomic prediction accuracy for meat tenderness in Nellore cattle using artificial neural networks. J Anim Breed Genet. 2020; 137(5):438-448. DOI: 10.1111/jbg.12468. View

15.

Killinger K, Calkins C, Umberger W, Feuz D, Eskridge K . Consumer visual preference and value for beef steaks differing in marbling level and color. J Anim Sci. 2004; 82(11):3288-93. DOI: 10.2527/2004.82113288x. View

16.

Cho S, Kang G, Seong P, Park B, Kang S . Effect of slaughter age on the antioxidant enzyme activity, color, and oxidative stability of Korean Hanwoo (Bos taurus coreanae) cow beef. Meat Sci. 2015; 108:44-9. DOI: 10.1016/j.meatsci.2015.05.018. View

17.

Wolfman N, McPherron A, Pappano W, Davies M, Song K, Tomkinson K . Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases. Proc Natl Acad Sci U S A. 2003; 100(26):15842-6. PMC: 307655. DOI: 10.1073/pnas.2534946100. View

18.

Allais S, Journaux L, Leveziel H, Payet-Duprat N, Raynaud P, Hocquette J . Effects of polymorphisms in the calpastatin and μ-calpain genes on meat tenderness in 3 French beef breeds. J Anim Sci. 2010; 89(1):1-11. DOI: 10.2527/jas.2010-3063. View

19.

Bellinge R, Liberles D, Iaschi S, OBrien P, Tay G . Myostatin and its implications on animal breeding: a review. Anim Genet. 2005; 36(1):1-6. DOI: 10.1111/j.1365-2052.2004.01229.x. View

20.

Tang L, Zhao T, Kang Y, An S, Fan X, Sun L . MSTN is an important myokine for weight-bearing training to attenuate bone loss in ovariectomized rats. J Physiol Biochem. 2021; 78(1):61-72. DOI: 10.1007/s13105-021-00838-5. View