Meibomian Gland Dysfunction Clinical Practice Guidelines

Overview

Journal Jpn J Ophthalmol

Specialty Ophthalmology

Date 2023 Jun 23

PMID 37351738

Authors

Shiro Amano

Jun Shimazaki

Norihiko Yokoi

Yuichi Hori

Reiko Arita

Affiliations

Soon will be listed here.

Citing Articles

Exploratory study on the efficacy of topical pan-JAK inhibitor in ocular and skin GVHD in a sclerodermatous GVHD mouse model.

Sato S, Ogawa Y, Asai K, Shimizu E, Shimizu S, Taniguchi H Sci Rep. 2025; 15(1):532.

PMID: 39748084 PMC: 11696563. DOI: 10.1038/s41598-024-84380-6.

Efficacy and safety of topical azithromycin therapy in patients with blepharitis and meibomian gland dysfunction.

Shimazaki J, Kito G, Kamoi M, Satake Y Jpn J Ophthalmol. 2024; 68(5):472-481.

PMID: 39002075 PMC: 11420373. DOI: 10.1007/s10384-024-01079-x.

The ILux compared to the mechanical meibomian gland expression for the treatment of moderate and severe meibomian gland dysfunction.

Nunez M, Acosta-Ortega A, Vera-Duarte G, Gomez-Duarte C Int J Ophthalmol. 2024; 17(6):1042-1048.

PMID: 38895679 PMC: 11144778. DOI: 10.18240/ijo.2024.06.08.

Standardization of meibomian gland dysfunction in an Egyptian population sample using a non-contact meibography technique.

Karara A, El-Sanabary Z, El-Helw M, Macky T, Abdelhakim M Int J Ophthalmol. 2024; 17(1):61-65.

PMID: 38239941 PMC: 10754661. DOI: 10.18240/ijo.2024.01.08.

The Yin and Yang of non-immune and immune responses in meibomian gland dysfunction.

Beatty C, Ruiz-Lozano R, Quiroga-Garza M, Perez V, Jester J, Saban D Ocul Surf. 2024; 32:81-90.

PMID: 38224775 PMC: 11881750. DOI: 10.1016/j.jtos.2024.01.004.

References

Nichols K, Foulks G, Bron A, Glasgow B, Dogru M, Tsubota K . The international workshop on meibomian gland dysfunction: executive summary. Invest Ophthalmol Vis Sci. 2011; 52(4):1922-9. PMC: 3072157. DOI: 10.1167/iovs.10-6997a. View

Hwang H, Parfitt G, Brown D, Jester J . Meibocyte differentiation and renewal: Insights into novel mechanisms of meibomian gland dysfunction (MGD). Exp Eye Res. 2017; 163:37-45. PMC: 5561533. DOI: 10.1016/j.exer.2017.02.008. View

Amano S, Inoue K . Clinic-Based Study on Meibomian Gland Dysfunction in Japan. Invest Ophthalmol Vis Sci. 2017; 58(2):1283-1287. DOI: 10.1167/iovs.16-21374. View

Amano S, Inoue K . Estimation of Prevalence of Meibomian Gland Dysfunction in Japan. Cornea. 2017; 36(6):684-688. DOI: 10.1097/ICO.0000000000001208. View

Arita R, Mizoguchi T, Kawashima M, Fukuoka S, Koh S, Shirakawa R . Meibomian Gland Dysfunction and Dry Eye Are Similar but Different Based on a Population-Based Study: The Hirado-Takushima Study in Japan. Am J Ophthalmol. 2019; 207:410-418. DOI: 10.1016/j.ajo.2019.02.024. View

Butovich I . Tear film lipids. Exp Eye Res. 2013; 117:4-27. PMC: 3844095. DOI: 10.1016/j.exer.2013.05.010. View

Butovich I . Meibomian glands, meibum, and meibogenesis. Exp Eye Res. 2017; 163:2-16. PMC: 5728685. DOI: 10.1016/j.exer.2017.06.020. View

McCulley J, Shine W . Meibomian gland function and the tear lipid layer. Ocul Surf. 2006; 1(3):97-106. DOI: 10.1016/s1542-0124(12)70138-6. View

Shimazaki J, Sakata M, Tsubota K . Ocular surface changes and discomfort in patients with meibomian gland dysfunction. Arch Ophthalmol. 1995; 113(10):1266-70. DOI: 10.1001/archopht.1995.01100100054027. View

10.

Korb D, Henriquez A . Meibomian gland dysfunction and contact lens intolerance. J Am Optom Assoc. 1980; 51(3):243-51. View

11.

Mathers W . Ocular evaporation in meibomian gland dysfunction and dry eye. Ophthalmology. 1993; 100(3):347-51. DOI: 10.1016/s0161-6420(93)31643-x. View

12.

Mathers W, Lane J . Meibomian gland lipids, evaporation, and tear film stability. Adv Exp Med Biol. 1998; 438:349-60. DOI: 10.1007/978-1-4615-5359-5_50. View

13.

Craig J, Nelson J, Azar D, Belmonte C, Bron A, Chauhan S . TFOS DEWS II Report Executive Summary. Ocul Surf. 2017; 15(4):802-812. DOI: 10.1016/j.jtos.2017.08.003. View

14.

Georgiev G, Eftimov P, Yokoi N . Structure-function relationship of tear film lipid layer: A contemporary perspective. Exp Eye Res. 2017; 163:17-28. DOI: 10.1016/j.exer.2017.03.013. View

15.

Suzuki T, Teramukai S, Kinoshita S . Meibomian glands and ocular surface inflammation. Ocul Surf. 2015; 13(2):133-49. DOI: 10.1016/j.jtos.2014.12.002. View

16.

Suzuki T . Inflamed Obstructive Meibomian Gland Dysfunction Causes Ocular Surface Inflammation. Invest Ophthalmol Vis Sci. 2018; 59(14):DES94-DES101. DOI: 10.1167/iovs.17-23345. View

17.

Arita R, Mori N, Shirakawa R, Asai K, Imanaka T, Fukano Y . Meibum Color and Free Fatty Acid Composition in Patients With Meibomian Gland Dysfunction. Invest Ophthalmol Vis Sci. 2015; 56(8):4403-12. DOI: 10.1167/iovs.14-16254. View

18.

Baudouin C, Messmer E, Aragona P, Geerling G, Akova Y, Benitez-Del-Castillo J . Revisiting the vicious circle of dry eye disease: a focus on the pathophysiology of meibomian gland dysfunction. Br J Ophthalmol. 2016; 100(3):300-6. PMC: 4789719. DOI: 10.1136/bjophthalmol-2015-307415. View

19.

Chhadva P, Goldhardt R, Galor A . Meibomian Gland Disease: The Role of Gland Dysfunction in Dry Eye Disease. Ophthalmology. 2017; 124(11S):S20-S26. PMC: 5685175. DOI: 10.1016/j.ophtha.2017.05.031. View

20.

Geerling G, Baudouin C, Aragona P, Rolando M, Boboridis K, Benitez-Del-Castillo J . Emerging strategies for the diagnosis and treatment of meibomian gland dysfunction: Proceedings of the OCEAN group meeting. Ocul Surf. 2017; 15(2):179-192. DOI: 10.1016/j.jtos.2017.01.006. View