Case Report: Early Detection of Lung Carcinoid in an Asymptomatic Individual by Blood-test Initiated PET-CT Imaging

Overview

Journal Front Oncol

Specialty Oncology

Date 2023 Jun 22

PMID 37346076

Authors

Simon Burg

Ralf Smeets

Martin Gosau

Katja Failing

Audrey Laure Celine Grust

Affiliations

Soon will be listed here.

Abstract

We present the case of a 53-year-old woman who was diagnosed with early-stage lung cancer by targeted cancer screening consisting of an immunological biopsy-based blood test followed by radiological imaging. The PanTum Detect blood test detects the biomarkers Apo10/DNaseX and Transketolase-like 1 (TKTL1) in circulating macrophage-like cells from peripheral blood samples to identify asymptomatic individuals with a high risk for malignancy. The elevated blood test values initiated an F-FDG PET/CT visualization for further clarification. In this case, imaging indicated a lung carcinoma in the right upper lobe. A biopsy confirmed the presence of a lung carcinoma, which was removed surgically. Histologic examination revealed a typical I A2 carcinoid, which was completely removed, making further therapy obsolete.

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