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Treatment of Difficult, Calcified Lesions: Plaque Modification Strategies

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Specialty Radiology
Date 2023 Jun 19
PMID 37333746
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Abstract

Endovascular management of peripheral arterial disease is continually evolving. Most changes focus on addressing the challenges that hinder optimal patient outcomes; one of the most significant is how to best treat calcified lesions. Hardened plaque results in a variety of technical issues including impaired device delivery, decreased luminal revascularization, poor stent expansion, heightened risk of in-stent stenosis or thrombosis, and increased procedural time and cost. For this reason, plaque modification devices have been developed to mitigate this issue. This paper will describe these strategies and provide the reader with an overview of devices that can be used to treat chronically hardened lesions.

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References
1.
Huang C, Wu I, Wu Y, Hwang J, Wang S, Chen W . Association of lower extremity arterial calcification with amputation and mortality in patients with symptomatic peripheral artery disease. PLoS One. 2014; 9(2):e90201. PMC: 3936008. DOI: 10.1371/journal.pone.0090201. View

2.
Fernandez N, McEnaney R, Marone L, Rhee R, Leers S, Makaroun M . Predictors of failure and success of tibial interventions for critical limb ischemia. J Vasc Surg. 2010; 52(4):834-42. PMC: 4076901. DOI: 10.1016/j.jvs.2010.04.070. View

3.
McKinsey J, Zeller T, Rocha-Singh K, Jaff M, Garcia L . Lower extremity revascularization using directional atherectomy: 12-month prospective results of the DEFINITIVE LE study. JACC Cardiovasc Interv. 2014; 7(8):923-33. DOI: 10.1016/j.jcin.2014.05.006. View

4.
Das T, Mustapha J, Indes J, Vorhies R, Beasley R, Doshi N . Technique optimization of orbital atherectomy in calcified peripheral lesions of the lower extremities: the CONFIRM series, a prospective multicenter registry. Catheter Cardiovasc Interv. 2013; 83(1):115-22. PMC: 4158859. DOI: 10.1002/ccd.25046. View

5.
Guzman R, Brinkley D, Schumacher P, Donahue R, Beavers H, Qin X . Tibial artery calcification as a marker of amputation risk in patients with peripheral arterial disease. J Am Coll Cardiol. 2008; 51(20):1967-74. PMC: 2836514. DOI: 10.1016/j.jacc.2007.12.058. View