Riboswitches, from Cognition to Transformation

Overview

Journal Synth Syst Biotechnol

Specialty Biotechnology

Date 2023 Jun 16

PMID 37325181

Authors

Jingdong Xu

Junyuan Hou

Mengnan Ding

Zhiwen Wang

Tao Chen

Affiliations

Soon will be listed here.

Abstract

Riboswitches are functional RNA elements that regulate gene expression by directly detecting metabolites. Twenty years have passed since it was first discovered, researches on riboswitches are becoming increasingly standardized and refined, which could significantly promote people's cognition of RNA function as well. Here, we focus on some representative orphan riboswitches, enumerate the structural and functional transformation and artificial design of riboswitches including the coupling with ribozymes, hoping to attain a comprehensive understanding of riboswitch research.

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