Health-Related Qualities of Life in School-Aged Children with Bronchopulmonary Dysplasia

Overview

Journal J Pediatr

Specialty Pediatrics

Date 2023 Jun 10

PMID 37301279

Authors

Gabriella Sierra

Jessica P Liu

Izabelle Ith

Divya Gudur

Deja Cunningham

Suzanne E Dahlberg

Kristyn Beam

Jonathan M Gaffin

Affiliations

Soon will be listed here.

Abstract

Objective: To determine health-related quality of life (HRQOL) of school-aged children with bronchopulmonary dysplasia (BPD) using the standardized Patient-Reported Outcomes Measurement Information System (PROMIS) assessment tools.

Study Design: The Indoor Air Quality and Respiratory Morbidity in Children with BPD Study is an ongoing observational study of school-aged children with BPD. HRQOL is assessed at enrollment by 3 PROMIS questionnaires, Parent Proxy Scale-Global Health 7, Parent Proxy Psychological Stress Experiences-Short Form, and the Parent Proxy Profile-Profile-25. PROMIS data were tested for significant deviation from the standardized T-Score references for normative populations of children.

Results: Eighty-nine subjects enrolled in the AERO-BPD study had complete outcome data for HRQOL. The mean age was 9 (±2) years and 43% were female. Mean days on respiratory support totaled 96 (±40). Across all domains, school-aged children with BPD reported similar or slightly better outcomes than the reference sample. Statistically significant findings of lower depression (P < .0001), fatigue (P < .0001), and pain (P < .0001) scores were found; there was no difference in psychological stress experiences (P = .87), global health (P = .06), anxiety (P = .08), relationships (P = .80), and mobility (P = .59) domains.

Conclusions: This study demonstrated that children with BPD may have less depression, fatigue, and pain HRQL than the general population. Once validated, these findings may offer reassurance to parents and providers caring for children with BPD.

Citing Articles

[Prognosis of bronchopulmonary dysplasia].

Zhou Y, Wang T, Fu X, Peng B, Fu Z Zhongguo Dang Dai Er Ke Za Zhi. 2025; 27(1):115-120.

PMID: 39825661 PMC: 11750241. DOI: 10.7499/j.issn.1008-8830.2406004.

Perception of quality of life in school-age children born before 32 weeks of gestational age.

Merino-Hernandez A, Munoz-Cutillas A, Ramos-Navarro C, Bellon-Alonso S, Rodriguez-Cimadevilla J, Gonzalez-Pacheco N Eur J Pediatr. 2024; 184(1):49.

PMID: 39604511 DOI: 10.1007/s00431-024-05882-z.

Moreno-Galarraga L, Liu J, Ith I, Cunningham D, Corrado R, Lee J Eur J Pediatr. 2024; 184(1):36.

PMID: 39567397 DOI: 10.1007/s00431-024-05878-9.

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