Purinergic Signalling in Physiology and Pathophysiology

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2023 Jun 10

PMID 37298149

Authors

Ronald Sluyter

Affiliations

Soon will be listed here.

Abstract

Since its inception by the late Geoffrey Burnstock in the early 1970s [...].

References

Hamoud A, Bach K, Kakrecha O, Henkel N, Wu X, McCullumsmith R . Adenosine, Schizophrenia and Cancer: Does the Purinergic System Offer a Pathway to Treatment?. Int J Mol Sci. 2022; 23(19). PMC: 9570456. DOI: 10.3390/ijms231911835. View

Cicero A, Fogacci F, Di Micoli V, Angeloni C, Giovannini M, Borghi C . Purine Metabolism Dysfunctions: Experimental Methods of Detection and Diagnostic Potential. Int J Mol Sci. 2023; 24(8). PMC: 10138451. DOI: 10.3390/ijms24087027. View

Volonte C, Alberti F, Vitale G, Liguori F . Delineating Purinergic Signaling in . Int J Mol Sci. 2022; 23(23). PMC: 9738970. DOI: 10.3390/ijms232315196. View

Li Y, Huang X, Fowler C, Lim Y, Laws S, Faux N . Identification of Leukocyte Surface P2X7 as a Biomarker Associated with Alzheimer's Disease. Int J Mol Sci. 2022; 23(14). PMC: 9322488. DOI: 10.3390/ijms23147867. View

Sophocleous R, Ooi L, Sluyter R . The P2X4 Receptor: Cellular and Molecular Characteristics of a Promising Neuroinflammatory Target. Int J Mol Sci. 2022; 23(10). PMC: 9147237. DOI: 10.3390/ijms23105739. View

Korb V, Schultz I, Beckenkamp L, Wink M . A Systematic Review of the Role of Purinergic Signalling Pathway in the Treatment of COVID-19. Int J Mol Sci. 2023; 24(9). PMC: 10178215. DOI: 10.3390/ijms24097865. View

Nishiyama K, Ariyoshi K, Nishimura A, Kato Y, Mi X, Kurose H . Knockout of Purinergic P2Y Receptor Fails to Improve Liver Injury and Inflammation in Non-Alcoholic Steatohepatitis. Int J Mol Sci. 2023; 24(4). PMC: 9963899. DOI: 10.3390/ijms24043800. View

Zhao Y, Ren W, Zhang Y, He J, Yin H, Liao Y . High, in Contrast to Low Levels of Acute Stress Induce Depressive-like Behavior by Involving Astrocytic, in Addition to Microglial P2X7 Receptors in the Rodent Hippocampus. Int J Mol Sci. 2022; 23(3). PMC: 8836505. DOI: 10.3390/ijms23031904. View

Campos-Contreras A, Gonzalez-Gallardo A, Diaz-Munoz M, Vazquez-Cuevas F . Adenosine Receptor A2B Negatively Regulates Cell Migration in Ovarian Carcinoma Cells. Int J Mol Sci. 2022; 23(9). PMC: 9100769. DOI: 10.3390/ijms23094585. View

10.

Hu X, Shi N, Zhang J, Zuo Y, Wang X, Zhao Y . CD73: Friend or Foe in Lung Injury. Int J Mol Sci. 2023; 24(6). PMC: 10056814. DOI: 10.3390/ijms24065545. View

11.

Huang Z, Xie N, Illes P, Di Virgilio F, Ulrich H, Semyanov A . From purines to purinergic signalling: molecular functions and human diseases. Signal Transduct Target Ther. 2021; 6(1):162. PMC: 8079716. DOI: 10.1038/s41392-021-00553-z. View

12.

Burnstock G . Purinergic Signalling: Therapeutic Developments. Front Pharmacol. 2017; 8:661. PMC: 5622197. DOI: 10.3389/fphar.2017.00661. View

13.

Vlajkovic S, Thorne P . Purinergic Signalling in the Cochlea. Int J Mol Sci. 2022; 23(23). PMC: 9741428. DOI: 10.3390/ijms232314874. View

14.

De Salis S, Li L, Chen Z, Lam K, Skarratt K, Balle T . Alternatively Spliced Isoforms of the P2X7 Receptor: Structure, Function and Disease Associations. Int J Mol Sci. 2022; 23(15). PMC: 9329894. DOI: 10.3390/ijms23158174. View

15.

Hutteau-Hamel T, Mellouk A, Trainel N, Cassard A, Bobe P . Hypercholesterolemia Negatively Regulates P2X7-Induced Cellular Function in CD4 and CD8 T-Cell Subsets from B6 Mice Fed a High-Fat Diet. Int J Mol Sci. 2022; 23(12). PMC: 9223416. DOI: 10.3390/ijms23126730. View

16.

Burnstock G . Purinergic nerves. Pharmacol Rev. 1972; 24(3):509-81. View

17.

Zuccarini M, Giuliani P, Ronci M, Caciagli F, Caruso V, Ciccarelli R . Purinergic Signaling in Oral Tissues. Int J Mol Sci. 2022; 23(14). PMC: 9318746. DOI: 10.3390/ijms23147790. View