Natural Products for the Prevention, Treatment and Progression of Breast Cancer

Overview

Journal Cancers (Basel)

Publisher MDPI

Specialty Oncology

Date 2023 Jun 10

PMID 37296944

Authors

Fabiano Svolacchia

Sergio Brongo

Alessia Catalano

Agostino Ceccarini

Lorenzo Svolacchia

Alessandro Santarsiere

Carmen Scieuzo

Rosanna Salvia

Francesca Finelli

Luigi Milella

Carmela Saturnino

Maria Stefania Sinicropi

Tommaso Fabrizio

Federica Giuzio

Affiliations

Soon will be listed here.

Abstract

In this review, we summarize the most used natural products as useful adjuvants in BC by clarifying how these products may play a critical role in the prevention, treatment and progression of this disease. BC is the leading cancer, in terms of incidence, that affects women. The epidemiology and pathophysiology of BC were widely reported. Inflammation and cancer are known to influence each other in several tumors. In the case of BC, the inflammatory component precedes the development of the neoplasm through a slowly increasing and prolonged inflammation that also favors its growth. BC therapy involves a multidisciplinary approach comprising surgery, radiotherapy and chemotherapy. There are numerous observations that showed that the effects of some natural substances, which, in integration with the classic protocols, can be used not only for prevention or integration in order to prevent recurrences and induce a state of chemoquiescence but also as chemo- and radiosensitizers during classic therapy.

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