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A Rare Radiological Presentation of Pulmonary Metastases from Malignant Melanoma

Overview
Journal Radiol Case Rep
Publisher Elsevier
Specialty Radiology
Date 2023 Jun 8
PMID 37287725
Authors
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Abstract

Malignant melanoma is a highly aggressive cancer with metastatic potential to various locations such as the lymph nodes, lungs, liver, brain, and bone. After the lymph nodes, the lungs are the most common site of malignant melanoma metastases. Pulmonary metastases from malignant melanoma commonly presents as solitary or multiple solid nodules, sub-solid nodules or miliary opacities on CT chest. We present a case of pulmonary metastases from malignant melanoma in a 74-year-old man which presented unusually on CT chest as a combination of patterns like "crazy paving," upper lobe predominance with subpleural sparing, and centrilobular micronodules. Video-assisted thoracoscopic surgery, wedge resection and tissue analysis were performed, which confirmed the diagnosis of malignant melanoma metastases, and the patient further underwent PET-CT for staging and surveillance. Patients with pulmonary metastases from malignant melanoma can have atypical imaging findings, therefore radiologists should be aware of these unconventional presentations to avoid any misdiagnoses.

References
1.
Okita R, Yamashita M, Nakata M, Teramoto N, Bessho A, Mogami H . Multiple ground-glass opacity in metastasis of malignant melanoma diagnosed by lung biopsy. Ann Thorac Surg. 2004; 79(1):e1-2. DOI: 10.1016/j.athoracsur.2004.03.096. View

2.
Choi Y, Chang Y, Kim S, Choe K, Lee K, An J . Crazy paving radiography finding in asymptomatic pulmonary alveolar proteinosis. Asian Cardiovasc Thorac Ann. 2014; 23(5):588-90. DOI: 10.1177/0218492314548232. View

3.
Mizuuchi H, Suda K, Kitahara H, Shimamatsu S, Kohno M, Okamoto T . Solitary pulmonary metastasis from malignant melanoma of the bulbar conjunctiva presenting as a pulmonary ground glass nodule: Report of a case. Thorac Cancer. 2015; 6(1):97-100. PMC: 4448462. DOI: 10.1111/1759-7714.12124. View

4.
Dalpiaz G, Asioli S, Fanti S, Rea G, Marchiori E . Rapidly growing pulmonary ground-glass nodule caused by metastatic melanoma lacking uptake on 18F-FDG PET-CT. J Bras Pneumol. 2018; 44(2):171-172. PMC: 6044662. DOI: 10.1590/s1806-37562017000000298. View

5.
Detterbeck F, Grodzki T, Gleeson F, Robert J . Imaging requirements in the practice of pulmonary metastasectomy. J Thorac Oncol. 2010; 5(6 Suppl 2):S134-9. DOI: 10.1097/JTO.0b013e3181dcf64d. View