A Meta-analysis of Optimum Level of Dietary Nanoselenium on Performances, Blood Constituents, Antioxidant Activity, Carcass, and Giblet Weight of Broiler Chickens

Overview

Journal Biol Trace Elem Res

Date 2023 Jun 3

PMID 37269453

Authors

Arif Darmawan

Minanur Rohman

Hidayatul Fitri

Anugrah Junaidi

Ridho Kurniawan Rusli

Ergin Ozturk

Affiliations

Soon will be listed here.

Abstract

Contradictory reports regarding the effects of nanoselenium (NanoSe) on the performance of broiler chickens may occur. Therefore, the optimum supplementation of NanoSe doses needs to be determined. The current meta-analysis study was aimed at evaluating the effectiveness and the optimum doses of NanoSe supplementation in broiler diets on performance, blood constituents, carcass, and giblet weight by considering breed and sex. The database was obtained from online scientific publications by searching through search engines such as Scopus, Web of Science, Google Scholar, and PubMed by entering the keywords nanoselenium, performance, antioxidants, and broiler. A total of 25 articles were included in the meta-analysis database. The study group was treated as a random effect while NanoSe dose, breed, and sex were treated as fixed effects. Daily body weight gain, carcass weight, and breast weight increased quadratically (P < 0.05), and FCR decreased quadratically (P < 0.05) in the starter and cumulative periods with increasing NanoSe supplementation. NanoSe supplementation tended to decrease cumulative feed intake linearly (P < 0.1) and decreased (P < 0.05) abdominal fat, albumin, red blood cells, ALT, and MDA levels. In contrast, levels of total protein, globulin, glucose, AST, white blood cells, cholesterol, triglyceride, and the weight of the liver, heart, gizzard, bursa of Fabricius, thymus, and spleen were not affected by NanoSe supplementation. Increasing the dose of NanoSe increased (P < 0.05) the GSHPx enzyme and Se concentration in breast muscle and liver and tended to enhance (P < 0.01) the CAT enzyme. It is concluded that a proper dose of NanoSe supplementation in a broiler diet improves body weight gain, feed efficiency, carcass, and breast weight without adverse effects on giblets. Dietary NanoSe elevates Se concentration in the breast muscle and liver and antioxidant activity. The current meta-analysis shows that the optimum dose for body weight gain and FCR is 1 to 1.5 mg/kg.

Citing Articles

Green synthesis of zinc oxide nanoparticles utilizing extract from leaves: Characterization and optimization of calcination temperature.

Rusli R, Hilmi M, Mahata M, Yuniza A, Zurmiati Z, Reski S J Adv Vet Anim Res. 2024; 11(3):573-582.

PMID: 39605758 PMC: 11590589. DOI: 10.5455/javar.2024.k807.

References

Teyssier J, Brugaletta G, Sirri F, Dridi S, Rochell S . A review of heat stress in chickens. Part II: Insights into protein and energy utilization and feeding. Front Physiol. 2022; 13:943612. PMC: 9393371. DOI: 10.3389/fphys.2022.943612. View

Lochi G, Shah M, Gandahi J, Gadahi J, Hadi S, Farooq T . Effect of Selenium Nanoparticles and Chitosan on Production Performance and Antioxidant Integrity of Heat-Stressed Broiler. Biol Trace Elem Res. 2022; 201(4):1977-1986. DOI: 10.1007/s12011-022-03262-y. View

Li J, Zhang L, Yang Z, Zhang Z, Jiang Y, Gao F . Effects of Different Selenium Sources on Growth Performance, Antioxidant Capacity and Meat Quality of Local Chinese Subei Chickens. Biol Trace Elem Res. 2017; 181(2):340-346. DOI: 10.1007/s12011-017-1049-4. View

Hu T, Liang Y, Zhao G, Wu W, Li H, Guo Y . Selenium Biofortification and Antioxidant Activity in Cordyceps militaris Supplied with Selenate, Selenite, or Selenomethionine. Biol Trace Elem Res. 2018; 187(2):553-561. DOI: 10.1007/s12011-018-1386-y. View

Lara L, Rostagno M . Impact of Heat Stress on Poultry Production. Animals (Basel). 2015; 3(2):356-69. PMC: 4494392. DOI: 10.3390/ani3020356. View

He X, Lin Y, Lian S, Sun D, Guo D, Wang J . Selenium Deficiency in Chickens Induces Intestinal Mucosal Injury by Affecting the Mucosa Morphology, SIgA Secretion, and GSH-Px Activity. Biol Trace Elem Res. 2020; 197(2):660-666. DOI: 10.1007/s12011-019-02017-6. View

Zainudin N, Hemly N, Muhammad A, Nayan N, Samsudin A . Effects of supplementing organic- and inorganic-based selenium with vitamin E on intestinal histomorphology, caecal bacterial proliferation, and short-chain fatty acid profile in layer hens. Trop Anim Health Prod. 2023; 55(2):90. DOI: 10.1007/s11250-023-03482-x. View

Safdari-Rostamabad M, Hosseini-Vashan S, Perai A, Sarir H . Nanoselenium Supplementation of Heat-Stressed Broilers: Effects on Performance, Carcass Characteristics, Blood Metabolites, Immune Response, Antioxidant Status, and Jejunal Morphology. Biol Trace Elem Res. 2016; 178(1):105-116. DOI: 10.1007/s12011-016-0899-5. View

Khazraei S, Tabeidian S, Habibian M . Selenium nanoparticles are more efficient than sodium selenite in reducing the toxicity of aflatoxin B in Japanese quail. Vet Med Sci. 2021; 8(1):254-266. PMC: 8788959. DOI: 10.1002/vms3.650. View

10.

Zhou J, Huang K, Lei X . Selenium and diabetes--evidence from animal studies. Free Radic Biol Med. 2013; 65:1548-1556. PMC: 3859733. DOI: 10.1016/j.freeradbiomed.2013.07.012. View

11.

Kim J, Choi S, Lee H, Hwang I, Lee Y, An B . Selenium significantly inhibits adipocyte hypertrophy and abdominal fat accumulation in OLETF rats via induction of fatty acid β-oxidation. Biol Trace Elem Res. 2012; 150(1-3):360-70. DOI: 10.1007/s12011-012-9519-1. View

12.

Al-Dwairi A, Pabona J, Simmen R, Simmen F . Cytosolic malic enzyme 1 (ME1) mediates high fat diet-induced adiposity, endocrine profile, and gastrointestinal tract proliferation-associated biomarkers in male mice. PLoS One. 2012; 7(10):e46716. PMC: 3464285. DOI: 10.1371/journal.pone.0046716. View

13.

Surai P, Kochish I, Velichko O . Nano-Se Assimilation and Action in Poultry and Other Monogastric Animals: Is Gut Microbiota an Answer?. Nanoscale Res Lett. 2017; 12(1):612. PMC: 5714942. DOI: 10.1186/s11671-017-2383-3. View

14.

Bierla K, Dernovics M, Vacchina V, Szpunar J, Bertin G, Lobinski R . Determination of selenocysteine and selenomethionine in edible animal tissues by 2D size-exclusion reversed-phase HPLC-ICP MS following carbamidomethylation and proteolytic extraction. Anal Bioanal Chem. 2008; 390(7):1789-98. DOI: 10.1007/s00216-008-1883-5. View

15.

Feng C, Lin H, Li J, Xie B . Effects of dietary inorganic chromium supplementation on broiler growth performance: a meta-analysis. PeerJ. 2021; 9:e11097. PMC: 7977379. DOI: 10.7717/peerj.11097. View

16.

Lv Q, Liang X, Nong K, Gong Z, Qin T, Qin X . Advances in Research on the Toxicological Effects of Selenium. Bull Environ Contam Toxicol. 2021; 106(5):715-726. DOI: 10.1007/s00128-020-03094-3. View

17.

Sun H, Rathinasabapathi B, Wu B, Luo J, Pu L, Ma L . Arsenic and selenium toxicity and their interactive effects in humans. Environ Int. 2014; 69:148-58. DOI: 10.1016/j.envint.2014.04.019. View

18.

Lazard M, Dauplais M, Blanquet S, Plateau P . Recent advances in the mechanism of selenoamino acids toxicity in eukaryotic cells. Biomol Concepts. 2017; 8(2):93-104. DOI: 10.1515/bmc-2017-0007. View

19.

Yildiz A, Kaya Y, Tanriverdi O . Effect of the Interaction Between Selenium and Zinc on DNA Repair in Association With Cancer Prevention. J Cancer Prev. 2019; 24(3):146-154. PMC: 6786808. DOI: 10.15430/JCP.2019.24.3.146. View

20.

El-Deep M, Ijiri D, Ebeid T, Ohtsuka A . Effects of Dietary Nano-Selenium Supplementation on Growth Performance, Antioxidative Status, and Immunity in Broiler Chickens under Thermoneutral and High Ambient Temperature Conditions. J Poult Sci. 2020; 53(4):274-283. PMC: 7477162. DOI: 10.2141/jpsa.0150133. View