Severe and Fatal Neonatal Infections Linked to a New Variant of Echovirus 11, France, July 2022 to April 2023

Overview

Journal Euro Surveill

Specialty Infectious Diseases

Date 2023 Jun 1

PMID 37261730

Authors

Mathilde Grapin

Audrey Mirand

Didier Pinquier

Aurelie Basset

Matthieu Bendavid

Maxime Bisseux

Marion Jeannoel

Berengere Kireche

Manoelle Kossorotoff

Anne-Sophie LHonneur

Lila Robin

Yves Ville

Sylvain Renolleau

Veronique Lemee

Pierre-Henri Jarreau

Isabelle Desguerre

Florence Lacaille

Marianne Leruez-Ville

Clemence Guillaume

Cecile Henquell

Alexandre Lapillonne

Isabelle Schuffenecker

Melodie Aubart

Affiliations

Soon will be listed here.

Abstract

We report nine severe neonatal infections caused by a new variant of echovirus 11. All were male, eight were twins. At illness onset, they were 3-5 days-old and had severe sepsis and liver failure. This new variant, detected in France since April 2022, is still circulating and has caused more fatal neonatal enterovirus infections in 2022 and 2023 (8/496; 1.6%, seven associated with echovirus 11) compared with 2016 to 2021 (7/1,774; 0.4%). National and international alerts are warranted.

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