Is Our Public Research Money Well Spent? Publication of Research Outputs from Health Research Council of New Zealand-funded Studies: a Cross-sectional Study

Overview

Journal BMJ Open

Specialty General Medicine

Date 2023 May 31

PMID 37258081

Authors

Marian Showell

Cynthia M Farquhar

Grace Greenwood

Vanessa M B Jordan

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate the reporting of results from the projects and programmes funded by the Health Research Council (HRC) New Zealand.

Design: A cross-sectional analysis.

Setting: Research projects and programmes funded by the HRC New Zealand from 2006 to 2014.

Participants: Publicly available data provided by the HRC.

Main Outcome Measures: The number and proportion with evidence of publication and dissemination of a research output from HRC grants and the time taken to disseminate the results.

Results: Of the 374 HRC grants from 2006 to 2014, there was no evidence of publication or reporting of any research output for 48 studies (13%). Of the 326 (87%) grants with research outputs, there was a mean dissemination time of 4.73 years (SD 2.37). The total funding provided by the HRC was NZ$471 663 336, while the 48 grants with no evidence of dissemination represented NZ$47 095 727 (10%).

Conclusions: Thirteen per cent of the HRC projects and programmes from 2006 to 2014 have not contributed to the healthcare evidence as their results remain unknown.

Citing Articles

Time to publication for results of clinical trials.

Showell M, Cole S, Clarke M, DeVito N, Farquhar C, Jordan V Cochrane Database Syst Rev. 2024; 11():MR000011.

PMID: 39601300 PMC: 11600493. DOI: 10.1002/14651858.MR000011.pub3.

References

Glasziou P, Altman D, Bossuyt P, Boutron I, Clarke M, Julious S . Reducing waste from incomplete or unusable reports of biomedical research. Lancet. 2014; 383(9913):267-76. DOI: 10.1016/S0140-6736(13)62228-X. View

Scherer R, Meerpohl J, Pfeifer N, Schmucker C, Schwarzer G, von Elm E . Full publication of results initially presented in abstracts. Cochrane Database Syst Rev. 2018; 11:MR000005. PMC: 7073270. DOI: 10.1002/14651858.MR000005.pub4. View

Sharma H, Verma S . Is positive publication bias really a bias, or an intentionally created discrimination toward negative results?. Saudi J Anaesth. 2019; 13(4):352-355. PMC: 6753760. DOI: 10.4103/sja.SJA_124_19. View

Wilson P, Petticrew M, Calnan M, Nazareth I . Does dissemination extend beyond publication: a survey of a cross section of public funded research in the UK. Implement Sci. 2010; 5:61. PMC: 2922079. DOI: 10.1186/1748-5908-5-61. View

Kerner J, Rimer B, Emmons K . Introduction to the special section on dissemination: dissemination research and research dissemination: how can we close the gap?. Health Psychol. 2005; 24(5):443-6. DOI: 10.1037/0278-6133.24.5.443. View

Jenkins V, Fallowfield L . For the Benefit of Others: Reasons Why Women with Breast Cancer Participate in RCTs. Breast Care (Basel). 2015; 10(2):88-93. PMC: 4464041. DOI: 10.1159/000376563. View

Ioannidis J . Effect of the statistical significance of results on the time to completion and publication of randomized efficacy trials. JAMA. 1998; 279(4):281-6. DOI: 10.1001/jama.279.4.281. View

Riveros C, Dechartres A, Perrodeau E, Haneef R, Boutron I, Ravaud P . Timing and completeness of trial results posted at ClinicalTrials.gov and published in journals. PLoS Med. 2013; 10(12):e1001566. PMC: 3849189. DOI: 10.1371/journal.pmed.1001566. View

Chinnery F, Young A, Goodman J, Ashton-Key M, Milne R . Time to publication for NIHR HTA programme-funded research: a cohort study. BMJ Open. 2013; 3(11):e004121. PMC: 3845050. DOI: 10.1136/bmjopen-2013-004121. View

10.

Brown J, Wakim P, Faraco C, Saugar-Lanchas C, Lungu C, Mendoza-Puccini C . Time to Publication of Clinical Trials Funded by the National Institute of Neurological Disorders and Stroke. Ann Neurol. 2021; 90(6):861-864. PMC: 8679128. DOI: 10.1002/ana.26246. View

11.

Ross J, Mulvey G, Hines E, Nissen S, Krumholz H . Trial publication after registration in ClinicalTrials.Gov: a cross-sectional analysis. PLoS Med. 2009; 6(9):e1000144. PMC: 2728480. DOI: 10.1371/journal.pmed.1000144. View

12.

Turner S, Wright D, Maeso R, Cook A, Milne R . Publication rate for funded studies from a major UK health research funder: a cohort study. BMJ Open. 2013; 3(5). PMC: 3646183. DOI: 10.1136/bmjopen-2012-002521. View

13.

Turner E, Matthews A, Linardatos E, Tell R, Rosenthal R . Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med. 2008; 358(3):252-60. DOI: 10.1056/NEJMsa065779. View

14.

Dickersin K, Min Y . NIH clinical trials and publication bias. Online J Curr Clin Trials. 1993; Doc No 50:[4967 words; 53 paragraphs]. View

15.

Strand L, Clarke P, Graves N, Barnett A . Time to publication for publicly funded clinical trials in Australia: an observational study. BMJ Open. 2017; 7(3):e012212. PMC: 5372122. DOI: 10.1136/bmjopen-2016-012212. View

16.

Wilson Archer S, Carlo W, Truog W, Stevenson D, Van Meurs K, Sanchez P . Improving publication rates in a collaborative clinical trials research network. Semin Perinatol. 2016; 40(6):410-417. PMC: 5192287. DOI: 10.1053/j.semperi.2016.05.003. View

17.

Chalmers I . Underreporting research is scientific misconduct. JAMA. 1990; 263(10):1405-8. View

18.

McElfish P, Purvis R, Stewart M, James L, Yeary K, Long C . Health Research Funding Agencies' Policies, Recommendations, and Tools for Dissemination. Prog Community Health Partnersh. 2019; 12(4):473-482. PMC: 7171974. DOI: 10.1353/cpr.2018.0072. View

19.

Tetroe J, Graham I, Foy R, Robinson N, Eccles M, Wensing M . Health research funding agencies' support and promotion of knowledge translation: an international study. Milbank Q. 2008; 86(1):125-55. PMC: 2690338. DOI: 10.1111/j.1468-0009.2007.00515.x. View

20.

Ross J, Tse T, Zarin D, Xu H, Zhou L, Krumholz H . Publication of NIH funded trials registered in ClinicalTrials.gov: cross sectional analysis. BMJ. 2012; 344:d7292. PMC: 3623605. DOI: 10.1136/bmj.d7292. View