The Clinical Pharmacology and Therapeutic Evaluation of Non-Steroidal Anti-Inflammatory Drugs in Adult Horses
Overview
Affiliations
This review firstly examines the underlying pathophysiology of pain and inflammation associated with orthopedic disease and endotoxemia. Then, it reviews the clinical pharmacology (pharmacokinetics and pharmacodynamics) of both conventional and non-conventional NSAIDs in the adult horse, and finally provides an overview of different modalities to evaluate the therapeutic efficacy of NSAIDs in research.
Costa G, Tabbi M, Bruschetta G, Spadola F, Leonardi F, Bruno F Front Vet Sci. 2025; 11:1505398.
PMID: 39742317 PMC: 11686550. DOI: 10.3389/fvets.2024.1505398.
Aragona F, Tabbi M, Gugliandolo E, Giannetto C, DAngelo F, Fazio F Front Vet Sci. 2024; 11:1496473.
PMID: 39720409 PMC: 11668182. DOI: 10.3389/fvets.2024.1496473.
Riley J, Chance L, Barshick M, Johnson S Transl Anim Sci. 2024; 8:txae153.
PMID: 39554613 PMC: 11568345. DOI: 10.1093/tas/txae153.
Interlandi C, Tabbi M, Di Pietro S, DAngelo F, Costa G, Arfuso F Front Vet Sci. 2024; 11:1341396.
PMID: 38379920 PMC: 10876772. DOI: 10.3389/fvets.2024.1341396.
Citarella G, Heitzmann V, Ranninger E, Bettschart-Wolfensberger R Animals (Basel). 2023; 13(22).
PMID: 38003065 PMC: 10668864. DOI: 10.3390/ani13223447.