Transforming Silver Nanoclusters from Racemic to Homochiral Via Seeded Crystallization

Overview

Journal J Phys Chem Lett

Publisher American Chemical Society

Specialty Chemistry

Date 2023 May 26

PMID 37234017

Authors

Along Ma

Wenjun Du

Jiawei Wang

Kefan Jiang

Cheng Zhang

Wenhan Sheng

Haiyan Zheng

Rongchao Jin

Shuxin Wang

Affiliations

Soon will be listed here.

Abstract

Chirality has risen as an attractive topic in materials research in recent years, but the attainment of enantiopure materials remains a major challenge. Herein, we obtained homochiral nanoclusters by a recrystallization strategy, without any chiral factors (i.e., chiral ligands, counterions, etc.). Through the rapid flipping of configuration of silver nanoclusters in solution, the initial racemic (triclinic) nanoclusters are converted to homochiral (orthorhombic) as revealed by X-ray crystallography. In the seeded crystallization, one homochiral crystal is used as a seed to direct the growth of crystals with specific chirality. Furthermore, enantiopure nanoclusters can be used as amplifiers for the detection of chiral carboxylic drugs. This work not only provides chiral conversion and amplification strategies to obtain homochiral nanoclusters but also explains the chirality origin of nanoclusters at the molecular level.

Citing Articles

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Jiang K, Ma A, Li Y, Wang J, Yin Z, Wang S RSC Adv. 2024; 14(15):10574-10579.

PMID: 38567326 PMC: 10985538. DOI: 10.1039/d4ra01274g.

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