Effect of Tumor Microenvironment on Ferroptosis: Inhibition or Promotion

Overview

Journal Front Oncol

Specialty Oncology

Date 2023 May 22

PMID 37213276

Authors

Zhengzhen Xia

Yi Quan

Affiliations

Soon will be listed here.

Abstract

Ferroptosis is a type of lipid peroxidation-induced, iron-dependent programmed cell death. Emerging evidence suggests that ferroptosis is intimately connected to tumorigenesis, development, treatment and plays a major role in tumor immune regulation. This study focused on the connection between ferroptosis and immune regulation, which may offer a theoretical basis for targeting ferroptosis and tumor immunotherapy.

Citing Articles

Ferroptosis in Pulmonary Disease and Lung Cancer: Molecular Mechanisms, Crosstalk Regulation, and Therapeutic Strategies.

Guo D, Cai S, Deng L, Xu W, Fu S, Lin Y MedComm (2020). 2025; 6(3):e70116.

PMID: 39991627 PMC: 11847630. DOI: 10.1002/mco2.70116.

Ferroptosis: A double-edged sword.

Wang S, Guo Q, Zhou L, Xia X Cell Death Discov. 2024; 10(1):265.

PMID: 38816377 PMC: 11139933. DOI: 10.1038/s41420-024-02037-9.

Ferroptosis and its current progress in gastric cancer.

Yue Z, Yuan Y, Zhou Q, Sheng J, Xin L Front Cell Dev Biol. 2024; 12:1289335.

PMID: 38481532 PMC: 10933004. DOI: 10.3389/fcell.2024.1289335.

Interplay of Ferroptosis and Cuproptosis in Cancer: Dissecting Metal-Driven Mechanisms for Therapeutic Potentials.

Wang J, Li J, Liu J, Chan K, Lee H, Lin K Cancers (Basel). 2024; 16(3).

PMID: 38339263 PMC: 10854932. DOI: 10.3390/cancers16030512.

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