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Rapid Determination of U/U in Urine Using Q-ICP-MS by a Simple Dilute-and-Shoot Approach

Overview
Publisher Springer
Specialty Chemistry
Date 2023 May 19
PMID 37206056
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Abstract

The measurement of uranium (U) isotope ratios in urine provides valuable information about the source of U exposure in humans and can be vitally important in a radiological emergency. This method provides rapid and accurate results for U/U at U concentrations as low as 0.42 ng/L, which is equivalent to ~200 ng/L of total U for a depleted U (DU) at a U/U ratio of ~0.002. The results are within 6% of Certified Reference Materials target values and agree with Department of Defense Armed Forces Institute of Pathology inter-laboratory comparison target values with a bias range of -6.9% to 7.6%.

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PMID: 39569318 PMC: 11578094. DOI: 10.1007/s10967-024-09656-7.

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