Post-COVID MRNA-vaccine IgG4 Shift: Worrisome?

Overview

Journal mSphere

Publisher American Society for Microbiology

Specialties Microbiology
Parasitology

Date 2023 May 16

PMID 37191589

Authors

Kamran Kadkhoda

Affiliations

Soon will be listed here.

Abstract

COVID-19 vaccines play a key role in ending the pandemic. Unraveling the immunological phenomena involved in offering protective immunity is the cornerstone of achieving such success. This perspective evaluates the possible mechanisms and implications of IgG4 production in response to mRNA-based COVID-19 vaccines.

Citing Articles

IgG Subclass Switch in Volunteers Repeatedly Immunized with the Full-Length Merozoite Surface Protein 1 (MSP1).

Rathay V, Furle K, Kiehl V, Ulmer A, Lanzer M, Thomson-Luque R Vaccines (Basel). 2024; 12(2).

PMID: 38400191 PMC: 10893298. DOI: 10.3390/vaccines12020208.

Atopy and Elevation of IgE, IgG3, and IgG4 May Be Risk Factors for Post COVID-19 Condition in Children and Adolescents.

Korner R, Bansemir O, Franke R, Sturm J, Dafsari H Children (Basel). 2023; 10(10).

PMID: 37892261 PMC: 10605545. DOI: 10.3390/children10101598.

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