The Role of Autotaxin and LPA Signaling in Embryonic Development, Pathophysiology and Cancer

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2023 May 13

PMID 37176032

Authors

Christiana Magkrioti

Eleanna Kaffe

Vassilis Aidinis

Affiliations

Soon will be listed here.

Abstract

Autotaxin (ATX) or Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 (ENPP2) is a secreted enzyme with lysophospholipase D activity, with its primary function being the extracellular hydrolysis of lysophosphatidylcholine (LPC) to lysophosphatidic acid (LPA), a bioactive lipid [...].

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