The Personalized Priority and Progress Questionnaire (PPPQ): A Personalized Instrument for Quality of Life and Self-management for Use in Clinical Trials and Practice

Overview

Journal Qual Life Res

Specialties Pharmacology
Rehabilitation Medicine

Date 2023 May 12

PMID 37171769

Authors

Judith Tommel

Cinderella K Cardol

Andrea W M Evers

Rianne Stuivenberg

Sandra van Dijk

Henriet van Middendorp

Affiliations

Soon will be listed here.

Abstract

Purpose: The aim of this study was to develop and validate a brief personalized instrument that (1) defines patients' priorities for improvement, (2) measures progress in prioritized quality of life (QoL) and self-management outcomes, and (3) is applicable in both clinical practice and clinical trials.

Methods: The instrument was developed based on the literature on personalized assessment and patient priorities, feedback by clinicians, and six cognitive interviews with patients with chronic kidney disease. The resulting questionnaire, the Personalized Priority and Progress Questionnaire (PPPQ), contains a baseline and follow-op measurement. The baseline measurement assesses functioning on QoL (8 items) and self-management (5 items). The final item evaluates patients' priorities for improvement. The follow-up measurement assesses progress in QoL and self-management. A personalized progress score can be calculated indicating the amount of progress on the QoL or self-management domain that is prioritized by the individual patient. Psychometric properties of the PPPQ were evaluated among patients with chronic kidney disease (n = 121) and patients with kidney failure treated with dialysis (n = 22).

Results: The PPPQ showed to be a feasible instrument that is easy and quick to complete. Regarding the construct validity, small to large correlations were found between the items and existing validated questionnaires measuring related constructs.

Conclusion: The PPPQ proved to be a feasible and valid instrument. The PPPQ can be adapted to match diverse populations and could be a useful tool both in clinical practice (e.g., to identify priorities and tailor treatment) and clinical trials (e.g., to evaluate the effectiveness of personalized interventions).

Citing Articles

E-HEalth treatment in Long-term Dialysis (E-HELD): study protocol for a multicenter randomized controlled trial evaluating personalized Internet-based cognitive-behavioral therapy in dialysis patients.

Tommel J, Evers A, van Hamersvelt H, van Dijk S, Chavannes N, Wirken L Trials. 2022; 23(1):477.

PMID: 35672832 PMC: 9172166. DOI: 10.1186/s13063-022-06392-9.

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