Vitamins As Regulators of Calcium-containing Kidney Stones - New Perspectives on the Role of the Gut Microbiome

Overview

Journal Nat Rev Urol

Specialty Urology

Date 2023 May 10

PMID 37161031

Authors

John A Chmiel

Gerrit A Stuivenberg

Kait F Al

Polycronis P Akouris

Hassan Razvi

Jeremy P Burton

Jennifer Bjazevic

Affiliations

Soon will be listed here.

Abstract

Calcium-based kidney stone disease is a highly prevalent and morbid condition, with an often complicated and multifactorial aetiology. An abundance of research on the role of specific vitamins (B, C and D) in stone formation exists, but no consensus has been reached on how these vitamins influence stone disease. As a consequence of emerging research on the role of the gut microbiota in urolithiasis, previous notions on the contribution of these vitamins to urolithiasis are being reconsidered in the field, and investigation into previously overlooked vitamins (A, E and K) was expanded. Understanding how the microbiota influences host vitamin regulation could help to determine the role of vitamins in stone disease.

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