Metabonomic Analysis of Tumor Microenvironments: a Mini-review

Overview

Journal Front Oncol

Specialty Oncology

Date 2023 May 1

PMID 37124524

Authors

Zeng Zeng

Cong-Xian Chen

Affiliations

Soon will be listed here.

Abstract

Metabolomic analysis is a vital part of studying cancer progression. Metabonomic crosstalk, such as nutrient availability, physicochemical transformation, and intercellular interactions can affect tumor metabolism. Many original studies have demonstrated that metabolomics is important in some aspects of tumor metabolism. In this mini-review, we summarize the definition of metabolomics and how it can help change a tumor microenvironment, especially in pathways of three metabonomic tumors. Just as non-invasive biofluids have been identified as early biomarkers of tumor development, metabolomics can also predict differences in tumor drug response, drug resistance, and efficacy. Therefore, metabolomics is important for tumor metabolism and how it can affect oncology drugs in cancer therapy.

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