Multifocal Cutaneous Phaeohyphomycosis Caused by with Clinical Resolution in an Immunocompromised Cat

Overview

Journal JFMS Open Rep

Date 2023 May 1

PMID 37123554

Authors

Jevgenija Kondratjeva

Charline Pressanti

Brice S Reynolds

Catherine Trumel

Maxence Delverdier

Anne-Cecile Normand

Nicolas Soetart

Jacques Guillot

Marie Christine Cadiergues

Affiliations

Soon will be listed here.

Abstract

Case Summary: A 3-year-old neutered domestic shorthair cat with a long history of idiopathic immune-mediated haemolytic anaemia and thrombocytopenia treated with ciclosporin and prednisolone was referred 2 months after the appearance of nodular dermatitis. A single pigmented nodule was present in the lateral carpal region of the right foreleg. The lesion was 7 mm in diameter, non-exudative and cutaneous to subcutaneous. Fine-needle aspiration of the mass revealed the presence of pigmented fungal elements. Excisional surgery was planned; in the meantime, a plaque-like lesion developed in the interorbital region. Histopathological examination confirmed the presumptive diagnosis of phaeohyphomycosis, and was identified as the aetiological agent. Itraconazole, given orally at a dose of 10 mg/kg for 8 weeks following surgery, enabled clinical resolution despite continued use of immunosuppressants. The follow-up was carried out over 14 weeks.

Relevance And Novel Information: This case report provides the first evidence of multifocal cutaneous phaeohyphomycosis caused by with clinical resolution after combined surgical and itraconazole treatment in an immunocompromised cat.

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