Folic Acid Adjustive Polydopamine Organic Nanoparticles Based Fluorescent Probe for the Selective Detection of Mercury Ions

Overview

Journal Polymers (Basel)

Publisher MDPI

Date 2023 Apr 28

PMID 37112040

Authors

Lijuan Chen

Changchang Chen

Yehan Yan

Linlin Yang

Renyong Liu

Jiajia Zhang

Xin Zhang

Chenggen Xie

Affiliations

Soon will be listed here.

Abstract

Polydopamine fluorescent organic nanomaterials present unique physicochemical and biological properties, which have great potential application in bio-imaging and chemical sensors. Here, folic acid (FA) adjustive polydopamine (PDA) fluorescent organic nanoparticles (FA-PDA FONs) were prepared by a facile one-pot self-polymerization strategy using dopamine (DA) and FA as precursors under mild conditions. The as-prepared FA-PDA FONs had an average size of 1.9 ± 0.3 nm in diameter with great aqueous dispersibility, and the FA-PDA FONs solution exhibit intense blue fluorescence under 365 nm UV lamp, and the quantum yield is ~8.27%. The FA-PDA FONs could be stable in a relatively wide pH range and high ionic strength salt solution, and the fluorescence intensities are constant. More importantly, here we developed a method for rapidly selective and sensitive detection of mercury ions (Hg) within 10 s using FA-PDA FONs based probe, the fluorescence intensities of FA-PDA FONs presented a great linear relationship to Hg concentration, the linear range and limit of detection (LOD) were 0-18 µM and 0.18 µM, respectively. Furthermore, the feasibility of the developed Hg sensor was verified by determination of Hg in mineral water and tap water samples with satisfactory results.

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