» Articles » PMID: 37111194

Effectiveness and Coverage of Severe Acute Malnutrition Treatment with a Simplified Protocol in a Humanitarian Context in Diffa, Niger

Abstract

Background: the aim of this study is to evaluate the effectiveness and coverage of a simplified protocol that is implemented in health centers (HCs) and health posts (HPs) for children who are suffering from severe acute malnutrition (SAM) in the humanitarian context of Diffa.

Methods: We conducted a non-randomized community-controlled trial. The control group received outpatient treatment for SAM, without medical complications, at HCs and HPs with the standard protocol of community management of acute malnutrition (CMAM). Meanwhile, with respect to the intervention group, the children with SAM received treatment at the HCs and HPs through a simplified protocol wherein the mid-upper arm circumference (MUAC) and the presence of edema were used as the admission criteria, and the children with SAM were administered doses of fixed ready-to-use therapeutic food (RUTF).

Results: A total of 508 children, who were all under 5 years and had SAM, were admitted into the study. The cured proportion was 87.4% in the control group versus 96.6% in the intervention group ( value = 0.001). There was no difference between the groups in the length of stay, which was 35 days, but the intervention group used a lower quantity of RUTF-70 sachets versus 90 sachets, per child cured. Coverage increases were observed in both groups.

Discussion: the simplified protocol used at the HCs and HPs did not result in worse recovery and resulted in fewer discharge errors compared to the standard protocol.

Citing Articles

Weight gain among children under five with severe malnutrition in therapeutic feeding programmes: a systematic review and meta-analysis.

ODonovan G, Allen D, Nkosi-Gondwe T, Anujuo K, Abera M, Kirolos A EClinicalMedicine. 2025; 81:103083.

PMID: 40026833 PMC: 11872456. DOI: 10.1016/j.eclinm.2025.103083.


Cost-effectiveness of decentralising acute malnutrition treatment with a standard or simplified treatment protocol: an economic evaluation in the region of Gao, Mali.

Cichon B, Lopez-Ejeda N, Samake S, Aton C, Dougnon A, Samake M BMC Public Health. 2025; 25(1):233.

PMID: 39833749 PMC: 11744804. DOI: 10.1186/s12889-025-21411-5.


Using Machine Learning to Fight Child Acute Malnutrition and Predict Weight Gain During Outpatient Treatment with a Simplified Combined Protocol.

Sanchez-Martinez L, Charle-Cuellar P, Gado A, Ousmane N, Hernandez C, Lopez-Ejeda N Nutrients. 2024; 16(23).

PMID: 39683605 PMC: 11644603. DOI: 10.3390/nu16234213.


Perceptions of stakeholders on the use of a simplified, combined protocol for treatment of acute malnutrition in Central African Republic.

Ngure F, Tausanovitch Z, Heymsfield G, Bebelou S, Seboulo P, Tabiojongmbeng B Matern Child Nutr. 2024; 21(1):e13743.

PMID: 39417422 PMC: 11650031. DOI: 10.1111/mcn.13743.


Improving case-detection of severe wasting among under-five-year-old children in Timor Leste: A secondary analysis of data from the 2020 national cross-sectional food and nutrition survey.

Mutunga M, Chiwile F, de Araujo Moniz N, Bahwere P PLoS One. 2024; 19(10):e0308208.

PMID: 39405267 PMC: 11478875. DOI: 10.1371/journal.pone.0308208.


References
1.
Rogers E, Myatt M, Woodhead S, Guerrero S, Alvarez J . Coverage of community-based management of severe acute malnutrition programmes in twenty-one countries, 2012-2013. PLoS One. 2015; 10(6):e0128666. PMC: 4456359. DOI: 10.1371/journal.pone.0128666. View

2.
de Onis M, Borghi E, Arimond M, Webb P, Croft T, Saha K . Prevalence thresholds for wasting, overweight and stunting in children under 5 years. Public Health Nutr. 2018; 22(1):175-179. PMC: 6390397. DOI: 10.1017/S1368980018002434. View

3.
Bailey J, Lelijveld N, Marron B, Onyoo P, Ho L, Manary M . Combined Protocol for Acute Malnutrition Study (ComPAS) in rural South Sudan and urban Kenya: study protocol for a randomized controlled trial. Trials. 2018; 19(1):251. PMC: 5978994. DOI: 10.1186/s13063-018-2643-2. View

4.
NDiaye D, Wassonguema B, Nikiema V, Kangas S, Salpeteur C . Economic evaluation of a reduced dosage of ready-to-use therapeutic foods to treat uncomplicated severe acute malnourished children aged 6-59 months in Burkina Faso. Matern Child Nutr. 2021; 17(3):e13118. PMC: 8189238. DOI: 10.1111/mcn.13118. View

5.
Kangas S, Marron B, Tausanovitch Z, Radin E, Andrianarisoa J, Dembele S . Effectiveness of Acute Malnutrition Treatment at Health Center and Community Levels with a Simplified, Combined Protocol in Mali: An Observational Cohort Study. Nutrients. 2022; 14(22). PMC: 9699530. DOI: 10.3390/nu14224923. View