[Obesity and Type 2 diabetes (Update 2023)]

Overview

Journal Wien Klin Wochenschr

Publisher Springer

Specialty General Medicine

Date 2023 Apr 26

PMID 37101029

Authors

Martin Clodi

Hermann Toplak

Michael Resl

Johanna Brix

Deborah Raphaela Leitner

Jurgen Harreiter

Friedrich Hoppichler

Thomas C Wascher

Karin Schindler

Bernhard Ludvik

Affiliations

Soon will be listed here.

Abstract

The body mass index (BMI) is a very crude measure of body fatness in individuals. Even normal weight persons can have too much body fat in cases of a lack of muscle mass (sarcopenia), which is why additional measurements of waist circumference and body fatness, e.g. bioimpedance analysis (BIA), are recommended. Lifestyle management including nutrition modification and increase in physical activity are important measures for the prevention and treatment of diabetes. Regarding the treatment of type 2 diabetes, body weight is increasingly used as a secondary target parameter. The choice of anti-diabetic treatment and additional concomitant therapies is increasingly influenced by body weight. The importance of modern GLP‑1 agonists and dual GLP‑1 GIP agonists increases since these drugs target obesity and type 2 diabetes. Bariatric surgery is at present indicated with a BMI > 35 kg/m with concomitant risk factors, such as diabetes and can lead at least to partial diabetes remission but has to be incorporated into an appropriate lifelong care concept.

Citing Articles

Vitamin D Alleviates Type 2 Diabetes Mellitus by Mitigating Oxidative Stress-Induced Pancreatic β-Cell Impairment.

Liu J, Zhang Y, Shi D, He C, Xia G Exp Clin Endocrinol Diabetes. 2023; 131(12):656-666.

PMID: 37935388 PMC: 10700019. DOI: 10.1055/a-2191-9969.

Enhancing Muscle Intracellular Ca Homeostasis and Glucose Uptake: Passive Pulsatile Shear Stress Treatment in Type 2 Diabetes.

Uryash A, Umlas J, Mijares A, Adams J, Lopez J Biomedicines. 2023; 11(10).

PMID: 37892970 PMC: 10604129. DOI: 10.3390/biomedicines11102596.

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