Reduced Bioavailability and Effect of Furosemide Given with Food

Overview

Journal Eur J Clin Pharmacol

Specialty Pharmacology

Date 1986 Jan 1

PMID 3709617

Citations 14

Authors

B BEERMANN

C Midskov

Affiliations

Soon will be listed here.

Abstract

10 healthy volunteers were given 40 mg furosemide p.o. with and without breakfast. The meal reduced the peak level of furosemide and decreased its bioavailability by approximately 30%. A heavy meal given to 5 of the subjects had no further effect. The reduced bioavailability caused a reduction in the diuretic effect.

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References

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