New Insights into Autophagy in Inflammatory Subtypes of Asthma

Overview

Journal Front Immunol

Specialty Allergy & Immunology

Date 2023 Apr 24

PMID 37090692

Authors

Hongna Dong

Wei Yang

Wei Li

Simin Zhu

Ling Zhu

Peng Gao

Yuqiu Hao

Affiliations

Soon will be listed here.

Abstract

Asthma is a heterogeneous airway disease characterized by airway inflammation and hyperresponsiveness. Autophagy is a self-degrading process that helps maintain cellular homeostasis. Dysregulation of autophagy is involved in the pathogenesis of many diseases. In the context of asthma, autophagy has been shown to be associated with inflammation, airway remodeling, and responsiveness to drug therapy. In-depth characterization of the role of autophagy in asthma can enhance the understanding of the pathogenesis, and provide a theoretical basis for the development of new biomarkers and targeted therapy for asthma. In this article, we focus on the relationship of autophagy and asthma, and discuss its implications for asthma pathogenesis and treatment.

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