» Articles » PMID: 37090317

A Rare Case of Polymyositis and Systemic Sclerosis Overlap Syndrome: Diagnosis and Treatment

Overview
Journal Cureus
Date 2023 Apr 24
PMID 37090317
Authors
Affiliations
Soon will be listed here.
Abstract

Diffuse scleroderma is a kind of scleroderma in which the immune system malfunctions, leading to excessive production of collagen in the skin and a variety of organ abnormalities. Based on previously recognized criteria, overlap syndrome is a disorder in which two or more medical illnesses are documented in a single patient. These syndromes are significantly more prevalent in illnesses with mixed connective tissue. In this case report, we present a patient with overlapping systemic sclerosis and polymyositis symptoms. The treatment and diagnosis of this extremely uncommon condition are discussed in further detail.

Citing Articles

Calcinosis Cutis in Juvenile Systemic Sclerosis.

Balaji D, Mohanasundaram K, Gopalakrishnan K Cureus. 2024; 16(5):e59729.

PMID: 38841009 PMC: 11151205. DOI: 10.7759/cureus.59729.

References
1.
Gordon S, Hughes J, Nee R, Stitt R, Bailey W, Little D . Systemic sclerosis medications and risk of scleroderma renal crisis. BMC Nephrol. 2019; 20(1):279. PMC: 6659266. DOI: 10.1186/s12882-019-1467-y. View

2.
Pope J, Denton C, Johnson S, Fernandez-Codina A, Hudson M, Nevskaya T . State-of-the-art evidence in the treatment of systemic sclerosis. Nat Rev Rheumatol. 2023; 19(4):212-226. PMC: 9970138. DOI: 10.1038/s41584-023-00909-5. View

3.
Danieli M, Fraticelli P, Salvi A, Gabrielli A, Danieli G . Undifferentiated connective tissue disease: natural history and evolution into definite CTD assessed in 84 patients initially diagnosed as early UCTD. Clin Rheumatol. 1998; 17(3):195-201. DOI: 10.1007/BF01451046. View

4.
Steen V . Autoantibodies in systemic sclerosis. Semin Arthritis Rheum. 2005; 35(1):35-42. DOI: 10.1016/j.semarthrit.2005.03.005. View

5.
Ghosh S, Sinha S, Thomas T, Sachdev H, Kurpad A . Revisiting Dietary Iron Requirement and Deficiency in Indian Women: Implications for Food Iron Fortification and Supplementation. J Nutr. 2019; 149(3):366-371. PMC: 6398383. DOI: 10.1093/jn/nxy283. View