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A Rare Case of Miller Fisher Syndrome in a 45-Year-Old Female

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Journal Cureus
Date 2023 Apr 24
PMID 37090296
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Abstract

Miller Fisher syndrome (MFS) is an uncommon form of Guillain-Barré syndrome (GBS), a neurological condition that is acquired, degenerative, demyelinating, and frequently characterized by gradual, symmetrical ascending paralysis. Ophthalmoplegia, ataxia, and areflexia are common symptoms that follow a bacterial or viral infection. Here, we want to draw attention to a rare case of MFS in a 45-year-old Indian female who had dysphagia, dysphasia, ataxia, and dyskinesia while moving around. Unusually, she had no past medical history of infection, recent vaccinations, upper respiratory tract infections, or any sexually transmitted diseases. Since this disorder has excellent prognosis, early diagnosis and effective treatment are crucial to minimizing unnecessary medical intervention and psychological suffering.

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References
1.
Fisher M . An unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmoplegia, ataxia and areflexia). N Engl J Med. 1956; 255(2):57-65. DOI: 10.1056/NEJM195607122550201. View

2.
Fujimura H . The Guillain-Barré syndrome. Handb Clin Neurol. 2013; 115:383-402. DOI: 10.1016/B978-0-444-52902-2.00021-7. View

3.
Head V, Wakerley B . Guillain-Barré syndrome in general practice: clinical features suggestive of early diagnosis. Br J Gen Pract. 2016; 66(645):218-9. PMC: 4809704. DOI: 10.3399/bjgp16X684733. View

4.
Mori M, Kuwabara S, Fukutake T, Yuki N, Hattori T . Clinical features and prognosis of Miller Fisher syndrome. Neurology. 2001; 56(8):1104-6. DOI: 10.1212/wnl.56.8.1104. View

5.
Liu J, Wang L, McNicol E . Pharmacological treatment for pain in Guillain-Barré syndrome. Cochrane Database Syst Rev. 2015; (4):CD009950. PMC: 6361619. DOI: 10.1002/14651858.CD009950.pub3. View